Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL230868 | 0.93 | MAPT (0.36) | MAP3K5MAP3K6 | |
| SCHEMBL232070 | 0.91 | MAP3K5 (0.41) | MAP3K5MAP3K6 | |
| SCHEMBL28657005 | 0.82 | ALDH1A1 (0.41) | MAP3K5 | |
| SCHEMBL28663394 | 0.80 | MAP3K5 (0.46) | MAP3K5MAP3K6 | |
| SCHEMBL233653 | 0.78 | MAP3K5 (0.44) | MAP3K5 | |
| SCHEMBL233897 | 0.75 | MAP3K5 (0.44) | MAP3K5MAP3K6 | |
| SCHEMBL28653523 | 0.74 | MAP3K5 (0.43) | MAP3K5 | |
| SCHEMBL10222850 | 0.72 | MAP3K5 (0.42) | MAP3K5MAP3K6 | |
| SCHEMBL28649130 | 0.68 | GRM5 (0.45) | MAP3K5 | |
| SCHEMBL28538145 | 0.68 | MAP3K5 (0.41) | MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588475-A1 | APOPTOSIS SIGNAL-REGULATING KINASE INHIBITORS | Gilead Sciences, Inc. (US) | 2013-05-08 | — | — | EP | disclosed |
| WO-2012003387-A1 | APOPTOSIS SIGNAL-REGULATING KINASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2012-01-05 | — | — | WO | disclosed |