Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.67 |
| ▸ | CCR2 | P41597 | 5/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19258581 | 0.83 | CA2 (0.60) | CA2CCR2AKR1B1CA9CA1 | |
| SCHEMBL7137894 | 0.83 | CA2 (0.71) | CA2CCR2AKR1B1CA9CA1 | |
| SCHEMBL329665 | 0.82 | CA2 (0.69) | CA2CCR2AKR1B1CA9CA1 | |
| SCHEMBL18184669 | 0.81 | CA2 (0.62) | CA2CCR2AKR1B1CA9CA1 | |
| SCHEMBL1655317 | 0.80 | CA2 (0.67) | CA2CCR2AKR1B1CA9CA1 | |
| SCHEMBL9063028 | 0.80 | CA2 (0.67) | CA2CCR2AKR1B1CA9CA1 | |
| SCHEMBL31695410 | 0.80 | CA2 (0.67) | CA2CCR2AKR1B1CA9CA1 | |
| SCHEMBL1156380 | 0.80 | CA2 (1.00) | CA2AKR1B1CA9CA1CA12 | |
| SCHEMBL720789 | 0.80 | CA2 (0.67) | CA2CCR2AKR1B1CA9CA1 | |
| SCHEMBL29926951 | 0.80 | CA2 (1.00) | CA2AKR1B1CA9CA1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10626112-B2 | Heterocyclic sulfonamide derivative and medicine comprising same | EA PHARMA CO., LTD. (JP) | 2020-04-21 | — | — | US | disclosed |
| US-20180162844-A1 | CYCLOPROPANE DERIVATIVE AND DRUG CONTAINING SAME | EA PHARMA CO., LTD. (JP) | 2018-06-14 | — | — | US | disclosed |
| US-20180162844-A1 | CYCLOPROPANE DERIVATIVE AND DRUG CONTAINING SAME | EA PHARMA CO., LTD. (JP) | 2018-06-14 | — | — | US | disclosed |
| US-20160332999-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVE AND MEDICINE COMPRISING SAME | EA PHARMA CO., LTD. (JP) | 2016-11-17 | — | — | US | disclosed |
| US-20160332999-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVE AND MEDICINE COMPRISING SAME | EA PHARMA CO., LTD. (JP) | 2016-11-17 | — | — | US | disclosed |
| WO-2015115507-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVE AND MEDICINE COMPRISING SAME | 味の素株式会社 | 2015-08-06 | — | — | WO | disclosed |
| CN-100335136-C | Pharmaceutical composition with reduced tendency for crystallization of drug | PHARMACIA CORP (US) | 2007-09-05 | — | — | CN | disclosed |
| CN-1498114-A | Pharmaceutical composition with reduced tendency for crystallization of drug | — | 2004-05-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160332999-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVE AND MEDICINE COMPRISING SAME | TRPA1, TRPV1, TRPV2 | CA2 210/4885CCR2 615/4885AKR1B1 1066/4885 |
| US-10626112-B2 | Heterocyclic sulfonamide derivative and medicine comprising same | TRPA1, TRPV1, TRPV2 | CA2 210/4885CCR2 615/4885AKR1B1 1066/4885 |
| US-20180162844-A1 | CYCLOPROPANE DERIVATIVE AND DRUG CONTAINING SAME | TRPA1, TRPV1, TRPV2 | CA2 834/4885CCR2 444/4885AKR1B1 1010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.