Cyclohexane

Cyclohexane

SCHEMBL1698647

C1CCCCC1.NC(N)=O

nearest known ligand 0.67

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.67
ALDH1A1 P00352 5/20 0.67
TDP1 Q9NUW8 2/20 0.67
OR51E2 Q9H255 1/20 0.67
ACHE P22303 1/20 0.46
BLM P54132 4/20 0.42
PMP22 Q01453 3/20 0.42
ALOX15 P16050 2/20 0.42
EPHX1 P07099 2/20 0.40
LDHA P00338 2/20 0.39
LDHB P07195 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.36
CYP3A4 P08684 3/20 0.36
TSHR P16473 3/20 0.36
NFKB1 P19838 2/20 0.36
HPGD P15428 2/20 0.36
HSD17B10 Q99714 2/20 0.36
CYP1A2 P05177 2/20 0.36
THPO P40225 2/20 0.36
EHMT2 Q96KQ7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexane SCHEMBL3125968 1.00 LMNA (0.67) LMNAALDH1A1TDP1OR51E2ACHE
Cycloheptane SCHEMBL1834654 1.00 LMNA (0.67) LMNAALDH1A1TDP1OR51E2ACHE
Cyclooctane SCHEMBL1841524 1.00 LMNA (0.67) LMNAALDH1A1TDP1OR51E2ACHE
Cyclohexane SCHEMBL1841235 1.00 LMNA (0.67) LMNAALDH1A1TDP1OR51E2ACHE
Cyclopentane SCHEMBL2745905 1.00
Urea SCHEMBL1411805 1.00
Urea SCHEMBL900201 1.00
Urea SCHEMBL11256077 0.95
Cyclopentane SCHEMBL9436973 0.95 LMNA (0.60) LMNAALDH1A1TDP1OR51E2ACHE
Cyclohexane SCHEMBL10769164 0.95 LMNA (0.60) LMNAALDH1A1TDP1OR51E2ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230110354-A1 THERAPEUTIC AGENT DELIVERY SYSTEMS AND METHODS OF FORMING AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE 2023-04-13 US claimed
WO-2021252897-A2 THERAPEUTIC AGENT DELIVERY SYSTEMS AND METHODS OF FORMING AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2021-12-16 WO claimed
CN-110372541-A A kind of method of carboxylic acid and the efficient synthesis in solid state amide derivatives of urea 南通市争妍新材料科技有限公司 2019-10-25 CN claimed
US-10251955-B1 Heparin-mimicking sulfonated reverse thermal gel for the delivery of heparin-binding therapeutic proteins THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2019-04-09 US claimed
US-9700628-B1 Heparin-mimicking sulfonated reverse thermal gel for the delivery of heparin-binding therapeutic proteins THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2017-07-11 US claimed
CN-102713033-B Spandex with high uniformity INVISTA TECH SARL 2015-04-15 CN claimed
CN-102713033-A Spandex with high uniformity INVISTA TECH SARL 2012-10-03 CN claimed
CN-101250162-A Preparation method of agricultural herbicide YANCHENG LVYE CHEMICAL INDUSTR (CN) 2008-08-27 CN claimed
US-12012478-B2 Carbon nanotube-functionalized reverse thermal gel and methods of forming and using same THE REGENTS OF THE UNIVERSITY OF COLORADO (US) 2024-06-18 US disclosed
US-20230220148-A1 CARBON NANOTUBE-FUNCTIONALIZED REVERSE THERMAL GEL AND METHODS OF FORMING AND USING SAME THE REGENTS OF THE UNIVERSITY OF COLORADO 2023-07-13 US disclosed
US-20230110354-A1 THERAPEUTIC AGENT DELIVERY SYSTEMS AND METHODS OF FORMING AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE 2023-04-13 US disclosed
US-11608407-B2 Carbon nanotube-functionalized reverse thermal gel and methods of forming and using same THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2023-03-21 US disclosed
WO-2021252897-A2 THERAPEUTIC AGENT DELIVERY SYSTEMS AND METHODS OF FORMING AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2021-12-16 WO disclosed
EP-3684501-A1 CARBON NANOTUBE-FUNCTIONALIZED REVERSE THERMAL GEL AND METHODS OF FORMING AND USING SAME The Regents of the University of Colorado, a body corporate (US) 2020-07-29 EP disclosed
EP-0174572-B1 CYCLOHEXANE-1,2-DICARBOXYLIC AMIDES, IONIC-SELECTIVES MEMBRANES AND TEST APPARATUS CONTAINING THESE COMPOUNDS Willi Möller AG (CH) 1991-03-06 EP disclosed
EP-0174572-A2 Cyclohexane-1,2-dicarboxylic amides, ionic-selectives membranes and test apparatus containing these compounds Willi Möller AG (CH) 1986-03-19 EP disclosed
EP-0174572-A2 Cyclohexane-1,2-dicarboxylic amides, ionic-selectives membranes and test apparatus containing these compounds Willi Möller AG (CH) 1986-03-19 EP disclosed
US-4217436-A N,N*-HYDROCARBYLENEDICARBONYLBIS/CYCLIC UREA/ THE UPJOHN COMPANY (US) 1980-08-12 US disclosed
US-4190599-A ACRYLATE COPOLYMER AND EPOXY RESIN THE UPJOHN COMPANY (US) 1980-02-26 US disclosed
US-4138398-A Bis-cyclic ureas THE UPJOHN COMPANY (US) 1979-02-06 US disclosed