Cyclopentane

Cyclopentane

SCHEMBL9436973

C1CCCC1.N.N.NC(N)=O

nearest known ligand 0.60

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.60
ALDH1A1 P00352 5/20 0.60
TDP1 Q9NUW8 2/20 0.60
OR51E2 Q9H255 1/20 0.60
ACHE P22303 1/20 0.42
BLM P54132 4/20 0.39
PMP22 Q01453 3/20 0.39
ALOX15 P16050 2/20 0.39
EPHX1 P07099 3/20 0.38
LDHA P00338 2/20 0.36
LDHB P07195 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
CYP3A4 P08684 3/20 0.33
TSHR P16473 3/20 0.33
NFKB1 P19838 2/20 0.33
HPGD P15428 2/20 0.33
HSD17B10 Q99714 2/20 0.33
CYP1A2 P05177 2/20 0.33
THPO P40225 2/20 0.33
EHMT2 Q96KQ7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexane SCHEMBL10769164 1.00 LMNA (0.60) LMNAALDH1A1TDP1OR51E2ACHE
Urea SCHEMBL1411805 0.95
Cyclohexane SCHEMBL1698647 0.95 LMNA (0.67) LMNAALDH1A1TDP1OR51E2ACHE
Cyclooctane SCHEMBL1841524 0.95 LMNA (0.67) LMNAALDH1A1TDP1OR51E2ACHE
Cyclohexane SCHEMBL1841235 0.95 LMNA (0.67) LMNAALDH1A1TDP1OR51E2ACHE
Cyclopentane SCHEMBL2745905 0.95
Urea SCHEMBL900201 0.95
Cyclohexane SCHEMBL3125968 0.95 LMNA (0.67) LMNAALDH1A1TDP1OR51E2ACHE
Cycloheptane SCHEMBL1834654 0.95 LMNA (0.67) LMNAALDH1A1TDP1OR51E2ACHE
Urea SCHEMBL11256077 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0211978-A1 Method for preparing a solventless thermoset polymeric composition Nichols, Gus (US) 1987-03-04 EP claimed
US-4547562-A Solventless polymeric composition comprising non arylamine, polyacrylate and epoxide NICHOLS GUS 1985-10-15 US claimed
EP-0211978-B1 Method for preparing a solventless thermoset polymeric composition NICHOLS GUS (US) 1994-07-20 EP disclosed
US-4675374-A Solventless polymeric composition reaction product of (1) adduct of amine and acrylate with (2) polyacrylate NICHOLS GUS 1987-06-23 US disclosed
EP-0211978-A1 Method for preparing a solventless thermoset polymeric composition Nichols, Gus (US) 1987-03-04 EP disclosed
US-4547562-A Solventless polymeric composition comprising non arylamine, polyacrylate and epoxide NICHOLS GUS 1985-10-15 US disclosed