⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexane SCHEMBL3125968 | 1.00 | LMNA (0.67) | — | |
| Cycloheptane SCHEMBL1834654 | 1.00 | LMNA (0.67) | — | |
| Cyclooctane SCHEMBL1841524 | 1.00 | LMNA (0.67) | — | |
| Cyclohexane SCHEMBL1698647 | 1.00 | LMNA (0.67) | — | |
| Cyclohexane SCHEMBL1841235 | 1.00 | LMNA (0.67) | — | |
| Urea SCHEMBL1411805 | 1.00 | — | — | |
| Urea SCHEMBL900201 | 1.00 | — | — | |
| Urea SCHEMBL11256077 | 0.95 | — | — | |
| Cyclopentane SCHEMBL9436973 | 0.95 | LMNA (0.60) | — | |
| Cyclohexane SCHEMBL10769164 | 0.95 | LMNA (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476428-B2 | Method of preparing cyclic carbonates, cyclic carbamates, cyclic ureas, cyclic thiocarbonates, cyclic thiocarbamates, and cyclic dithiocarbonates | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-07-02 | — | — | US | claimed |
| US-20120202993-A1 | METHOD OF PREPARING CYCLIC CARBONATES, CYCLIC CARBAMATES, CYCLIC UREAS, CYCLIC THIOCARBONATES, CYCLIC THIOCARBAMATES, AND CYCLIC DITHIOCARBONATES | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-08-09 | — | — | US | claimed |
| CN-101993416-A | Quinoline compound and preparation method thereof, medicament combination containing compound and application of compound | SHANGHAI INST MATERIA MEDICA | 2011-03-30 | — | — | CN | claimed |
| US-20100280242-A1 | Method of Preparing Cyclic Carbonates, Cyclic Carbamates, Cyclic Ureas, Cyclic Thiocarbonates, Cyclic Thiocarbamates, and Cyclic Dithiocarbonates | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2010-11-04 | — | — | US | claimed |
| US-8754208-B2 | Method of preparing cyclic carbonates, cyclic carbamates, cyclic ureas, cyclic thiocarbonates, cyclic thiocarbamates, and cyclic dithiocarbonates | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-06-17 | — | — | US | disclosed |
| US-20130237701-A1 | METHOD OF PREPARING CYCLIC CARBONATES, CYCLIC CARBAMATES, CYCLIC UREAS, CYCLIC THIOCARBONATES, CYCLIC THIOCARBAMATES, AND CYCLIC DITHIOCARBONATES | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-09-12 | — | — | US | disclosed |
| CN-101993416-B | Quinoline compound and preparation method thereof, medicament combination containing compound and application of compound | SHANGHAI INST MATERIA MEDICA | 2013-09-11 | — | — | CN | disclosed |
| US-8476428-B2 | Method of preparing cyclic carbonates, cyclic carbamates, cyclic ureas, cyclic thiocarbonates, cyclic thiocarbamates, and cyclic dithiocarbonates | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-07-02 | — | — | US | disclosed |
| US-20120202993-A1 | METHOD OF PREPARING CYCLIC CARBONATES, CYCLIC CARBAMATES, CYCLIC UREAS, CYCLIC THIOCARBONATES, CYCLIC THIOCARBAMATES, AND CYCLIC DITHIOCARBONATES | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-08-09 | — | — | US | disclosed |
| US-8178700-B2 | Method of preparing cyclic carbonates, cyclic carbamates, cyclic ureas, cyclic thiocarbonates, cyclic thiocarbamates, and cyclic dithiocarbonates | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-05-15 | — | — | US | disclosed |
| CN-101993416-A | Quinoline compound and preparation method thereof, medicament combination containing compound and application of compound | SHANGHAI INST MATERIA MEDICA | 2011-03-30 | — | — | CN | disclosed |
| US-20100280242-A1 | Method of Preparing Cyclic Carbonates, Cyclic Carbamates, Cyclic Ureas, Cyclic Thiocarbonates, Cyclic Thiocarbamates, and Cyclic Dithiocarbonates | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2010-11-04 | — | — | US | disclosed |
| US-4217436-A | N,N*-HYDROCARBYLENEDICARBONYLBIS/CYCLIC UREA/ | THE UPJOHN COMPANY (US) | 1980-08-12 | — | — | US | disclosed |
| US-4190599-A | ACRYLATE COPOLYMER AND EPOXY RESIN | THE UPJOHN COMPANY (US) | 1980-02-26 | — | — | US | disclosed |
| US-4138398-A | Bis-cyclic ureas | THE UPJOHN COMPANY (US) | 1979-02-06 | — | — | US | disclosed |