Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29792058 | 0.87 | DUT (0.32) | — | |
| SCHEMBL24618695 | 0.87 | DUT (0.32) | — | |
| SCHEMBL947122 | 0.84 | BACE1 (0.36) | IRAK4BACE1KCNH2 | |
| SCHEMBL28897081 | 0.83 | KCNH2 (0.35) | KCNH2BTK | |
| SCHEMBL20436465 | 0.83 | BACE1 (0.35) | IRAK4BACE1KCNH2 | |
| SCHEMBL24915289 | 0.82 | KDM4E (0.38) | IRAK4BACE1KCNH2 | |
| SCHEMBL28521511 | 0.80 | IRAK4 (0.36) | IRAK4BACE1KCNH2 | |
| SCHEMBL20416847 | 0.77 | KCNH2 (0.39) | IRAK4BACE1KCNH2 | |
| SCHEMBL15968790 | 0.77 | MEN1 (0.39) | IRAK4BACE1KCNH2 | |
| SCHEMBL20436590 | 0.77 | KCNH2 (0.39) | IRAK4BACE1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150225404-A1 | PYRIDINE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU CO., LTD. (JP) | 2015-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150225404-A1 | PYRIDINE DERIVATIVE AND MEDICINE | TRPV1, TRPV5, TRPM5 | IRAK4 346/4885BACE1 3758/4885KCNH2 755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.