SCHEMBL16989282

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16991862	0.84	KDM4E (0.56)	KLKB1NPC1KDM4EASPHKDM8
	SCHEMBL18476454	0.76	CYP2C9 (0.37)	ALDH1A1
	SCHEMBL16856919	0.75	MAPT (0.52)	NPC1KDM4EASPHKDM8VNN1
	SCHEMBL31289746	0.73	VNN1 (0.46)	KLKB1F2KDM4EASPHKDM8
	SCHEMBL31184855	0.72	THRB (0.55)	NPC1KDM4EASPHKDM8VNN1
	SCHEMBL18088826	0.72	VNN1 (0.45)	KLKB1F2NPC1KDM4EASPH
	SCHEMBL29142175	0.72	NPC1 (0.47)	KLKB1F2NPC1KDM4EASPH
	SCHEMBL31289825	0.71	PTK2 (0.43)	KLKB1F2KDM4EASPHKDM8
	SCHEMBL28283742	0.71	NPC1 (0.64)	NPC1CLK4MAPTEGFRPOLB
	SCHEMBL31184956	0.70	ATR (0.52)	KDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.