Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELL | P14151 | 1/20 | 0.46 |
| ▸ | SELP | P16109 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18732057 | 1.00 | SELL (0.46) | SELLSELPHDAC1GAAKDM1A | |
| SCHEMBL18732063 | 1.00 | SELL (0.46) | SELLSELPHDAC1GAAKDM1A | |
| SCHEMBL9313492 | 0.84 | LMNA (0.46) | GAAKDM1AL3MBTL1LMNARECQL | |
| SCHEMBL18717468 | 0.73 | ESR1 (0.48) | SELLSELPHDAC1L3MBTL1PIK3CA | |
| SCHEMBL896864 | 0.71 | SELL (0.50) | SELLSELPHDAC1PIK3CARECQL | |
| SCHEMBL924425 | 0.71 | SELL (0.62) | SELLSELPHDAC1PIK3CARECQL | |
| SCHEMBL7032709 | 0.71 | SELL (0.50) | SELLSELPHDAC1LMNAPIK3CA | |
| SCHEMBL9312464 | 0.71 | GAA (0.42) | GAAKDM1AL3MBTL1LMNARECQL | |
| SCHEMBL3082608 | 0.70 | HPGD (0.54) | GAAKDM1AL3MBTL1LMNAPIK3CA | |
| SCHEMBL12159938 | 0.70 | HPGD (0.54) | GAAKDM1AL3MBTL1LMNAPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0144396-B1 | POLYHYDROXYBENZOIC ACID DERIVATIVES | VAN'T RIET, Bartholomeus (US) | 1991-01-02 | — | — | EP | claimed |
| US-4623659-A | RIBONUCLEOTIDE REDUCTASE INHIBITORS | RIET BARTHOLOMEUS VAN T (US) | 1986-11-18 | — | — | US | claimed |
| EP-0144396-A4 | POLYHYDROXYBENZOIC ACID DERIVATIVES. | RIET BARTHOLOMEUS VAN T (US) | 1986-08-21 | — | — | EP | claimed |
| EP-0144396-A1 | POLYHYDROXYBENZOIC ACID DERIVATIVES. | RIET BARTHOLOMEUS VAN T (US) | 1985-06-19 | — | — | EP | claimed |
| WO-1984004676-A1 | POLYHYDROXYBENZOIC ACID DERIVATIVES | RIET BARTHOLOMEUS VAN T | 1984-12-06 | — | — | WO | claimed |
| US-20140349969-A1 | COMPOUNDS AND METHODS FOR TREATING PAIN | AKRON MOLECULES AG (AT) | 2014-11-27 | — | — | US | disclosed |
| US-20130252924-A1 | Compounds and Methods for Treating Pain | AKRON MOLECULES GMBH (AT) | 2013-09-26 | — | — | US | disclosed |
| US-20130178517-A1 | Methods And Compositions For Treatment Of Lipogenic Virus Related Conditions | OBETECH LLC | 2013-07-11 | — | — | US | disclosed |
| WO-2012006550-A2 | METHODS AND COMPOSITIONS FOR TREATMENT OF LIPOGENIC VIRUS RELATED CONDITIONS | OBETECH LLC (US) | 2012-01-12 | — | — | WO | disclosed |
| US-5366996-A | Administering hydroxamic acids | ELFORD HOWARD L (US) | 1994-11-22 | — | — | US | disclosed |
| US-5183828-A | Ribonucleotide reductase inhibitor and free radical scavenger | RIET BARTHOLOMEUS VAN T (US) | 1993-02-02 | — | — | US | disclosed |
| EP-0144396-B1 | POLYHYDROXYBENZOIC ACID DERIVATIVES | VAN'T RIET, Bartholomeus (US) | 1991-01-02 | — | — | EP | disclosed |
| US-4942253-A | INHIBITORS OF RIBONUCLEOTIDE REDUCTASE, ANTITUMOR AGENTS, LEUKEMIA, FREE RADICAL SCAVENGERS | RIET BARTHOLOMEUS VAN T (US) | 1990-07-17 | — | — | US | disclosed |
| US-4623659-A | RIBONUCLEOTIDE REDUCTASE INHIBITORS | RIET BARTHOLOMEUS VAN T (US) | 1986-11-18 | — | — | US | disclosed |
| EP-0144396-A4 | POLYHYDROXYBENZOIC ACID DERIVATIVES. | RIET BARTHOLOMEUS VAN T (US) | 1986-08-21 | — | — | EP | disclosed |
| EP-0144396-A1 | POLYHYDROXYBENZOIC ACID DERIVATIVES. | RIET BARTHOLOMEUS VAN T (US) | 1985-06-19 | — | — | EP | disclosed |
| WO-1984004676-A1 | POLYHYDROXYBENZOIC ACID DERIVATIVES | RIET BARTHOLOMEUS VAN T | 1984-12-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140349969-A1 | COMPOUNDS AND METHODS FOR TREATING PAIN | TRPV1, ACHE, OPRL1 | SELL 1471/4885SELP 987/4885HDAC1 1969/4885 |
| US-20130252924-A1 | Compounds and Methods for Treating Pain | TRPV1, ACHE, OPRL1 | SELL 1471/4885SELP 987/4885HDAC1 1969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.