Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 3/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.35 |
| ▸ | KDM1A | O60341 | 8/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18732057 | 0.71 | SELL (0.46) | GAAKDM1ARECQLLMNAL3MBTL1 | |
| SCHEMBL18732063 | 0.71 | SELL (0.46) | GAAKDM1ARECQLLMNAL3MBTL1 | |
| SCHEMBL1699097 | 0.71 | SELL (0.46) | GAAKDM1ARECQLLMNAL3MBTL1 | |
| SCHEMBL10180582 | 0.71 | GAA (0.40) | GAAESR1ESR2KDM1ALMNA | |
| SCHEMBL3455633 | 0.71 | GAA (0.40) | GAAESR1ESR2KDM1ALMNA | |
| SCHEMBL13926729 | 0.71 | GAA (0.40) | GAAESR1ESR2KDM1ALMNA | |
| SCHEMBL18717467 | 0.70 | RECQL (0.50) | GAAKDM1ARECQLLMNAL3MBTL1 | |
| SCHEMBL4168972 | 0.70 | RECQL (0.50) | GAAKDM1ARECQLLMNAL3MBTL1 | |
| SCHEMBL4168968 | 0.70 | RECQL (0.50) | GAAKDM1ARECQLLMNAL3MBTL1 | |
| SCHEMBL9313492 | 0.70 | LMNA (0.46) | GAAKDM1ARECQLLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5366996-A | Administering hydroxamic acids | ELFORD HOWARD L (US) | 1994-11-22 | — | — | US | disclosed |
| US-5183828-A | Ribonucleotide reductase inhibitor and free radical scavenger | RIET BARTHOLOMEUS VAN T (US) | 1993-02-02 | — | — | US | disclosed |
| US-4942253-A | INHIBITORS OF RIBONUCLEOTIDE REDUCTASE, ANTITUMOR AGENTS, LEUKEMIA, FREE RADICAL SCAVENGERS | RIET BARTHOLOMEUS VAN T (US) | 1990-07-17 | — | — | US | disclosed |
| US-4623659-A | RIBONUCLEOTIDE REDUCTASE INHIBITORS | RIET BARTHOLOMEUS VAN T (US) | 1986-11-18 | — | — | US | disclosed |