SCHEMBL16991973

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20341354	0.87	HSD17B10 (0.48)	NPC1PKMRAB9AACHEBACE1
	SCHEMBL16992006	0.83	NPC1 (0.62)	NPC1PKMRAB9AACHEBACE1
	SCHEMBL18310129	0.83	NPC1 (0.62)	NPC1PKMRAB9AACHEBACE1
	SCHEMBL22842802	0.73	SLC6A2 (0.52)	NPC1RAB9AALDH1A1SMN1; SMN2CHEK1
	SCHEMBL6336112	0.72	ERCC1 (0.69)	NPC1PKMRAB9AACHEBACE1
	SCHEMBL23292497	0.72	SMN1; SMN2 (0.57)	NPC1PKMRAB9AALDH1A1SMN1; SMN2
	SCHEMBL138885	0.72	IDO1 (0.50)	NPC1RAB9AACHEALDH1A1SMN1; SMN2
	SCHEMBL3437003	0.71	ALDH1A1 (0.66)	ALDH1A1SMN1; SMN2POLBTSHRMAPK10
	SCHEMBL22828868	0.71	SMN1; SMN2 (0.38)	NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
	SCHEMBL16992003	0.71	PDE4A (0.44)	PKMALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.