Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1699363 | 0.84 | KDM4C (0.39) | KDM4C | |
| SCHEMBL9981014 | 0.78 | ADORA3 (0.38) | DRD1MEN1KMT2APOLBPABPC1 | |
| SCHEMBL14889112 | 0.77 | DRD1 (0.38) | DRD1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL12045529 | 0.75 | LTA4H (0.43) | ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1701784 | 0.74 | LTA4H (0.42) | ALDH1A1MEN1KMT2A | |
| SCHEMBL9981008 | 0.74 | LTA4H (0.41) | MEN1KMT2A | |
| SCHEMBL1699182 | 0.74 | NPC1 (0.37) | ALDH1A1MEN1KMT2APKMTSHR | |
| SCHEMBL9981668 | 0.73 | GABRP (0.51) | — | |
| SCHEMBL1699077 | 0.73 | MAP3K11 (0.39) | ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL1699098 | 0.72 | DRD1 (0.44) | DRD1MEN1KMT2APOLBPABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011163355-A1 | FUSED HETEROCYCLIC COMPOUNDS AS PHOSPHODIESTERASES (PDES) INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-12-29 | — | — | WO | disclosed |