Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | HMOX1 | P09601 | 2/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | CTSV | O60911 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1699530 | 0.84 | CYP1A2 (0.45) | MAOBPLATALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL14889030 | 0.73 | HRH3 (0.42) | MAOBHRH3HMOX1PDE2AFFAR1 | |
| SCHEMBL4340540 | 0.71 | LMNA (0.60) | MAOBCYP1A2CYP2C19LMNAHIF1A | |
| SCHEMBL1699299 | 0.70 | NPC1 (0.45) | MAOBNPC1RAB9AL3MBTL1 | |
| SCHEMBL1699357 | 0.69 | PRMT5 (0.50) | ALDH1A1CYP1A2CYP2C9TSHRCYP2C19 | |
| SCHEMBL9981622 | 0.68 | NPC1 (0.58) | MAOBALDH1A1CTSVCTSLMEN1 | |
| SCHEMBL1699176 | 0.66 | NPC1 (0.49) | MAOBCTSVCTSLMEN1KMT2A | |
| SCHEMBL1699265 | 0.65 | NPC1 (0.46) | MAOBALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL24861854 | 0.64 | MAOB (0.62) | MAOB | |
| SCHEMBL29192686 | 0.64 | MAOB (0.76) | MAOBCTSVCTSLMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011163355-A1 | FUSED HETEROCYCLIC COMPOUNDS AS PHOSPHODIESTERASES (PDES) INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-12-29 | — | — | WO | disclosed |