Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1709041 | 0.85 | ACKR3 (0.31) | — | |
| SCHEMBL26528666 | 0.78 | DRD3 (0.41) | — | |
| SCHEMBL28124717 | 0.77 | ACKR3 (0.31) | — | |
| SCHEMBL8260670 | 0.74 | NSD2 (0.30) | — | |
| SCHEMBL18806147 | 0.74 | NSD2 (0.30) | — | |
| SCHEMBL18806186 | 0.74 | NSD2 (0.30) | — | |
| SCHEMBL16993387 | 0.73 | HPGD (0.48) | — | |
| SCHEMBL21569678 | 0.73 | ALDH1A1 (0.41) | — | |
| SCHEMBL21569672 | 0.72 | HSD11B1 (0.31) | — | |
| SCHEMBL16904633 | 0.72 | MCHR1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3102577-A1 | QUINOLONE DERIVATIVES AS FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITORS | Principia Biopharma Inc. (US) | 2016-12-14 | — | — | EP | disclosed |
| WO-2015120049-A1 | QUINOLONE DERIVATIVES AS FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITORS | PRINCIPIA BIOPHARMA, INC. (US) | 2015-08-13 | — | — | WO | disclosed |