Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 19/20 | 0.41 |
| ▸ | DRD2 | P14416 | 7/20 | 0.41 |
| ▸ | DRD4 | P21917 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1709041 | 0.83 | ACKR3 (0.31) | — | |
| SCHEMBL21039530 | 0.79 | CHI3L1 (0.37) | — | |
| SCHEMBL16993155 | 0.78 | CHIT1 (0.30) | — | |
| SCHEMBL688629 | 0.77 | DRD3 (0.45) | DRD3DRD2DRD4 | |
| SCHEMBL25788547 | 0.77 | DRD3 (0.32) | DRD3DRD2DRD4 | |
| SCHEMBL17282044 | 0.77 | KMT2A (0.36) | — | |
| SCHEMBL17281942 | 0.76 | SMN1; SMN2 (0.40) | — | |
| SCHEMBL688628 | 0.75 | DRD3 (0.44) | DRD3DRD2DRD4 | |
| SCHEMBL12104157 | 0.75 | DRD3 (0.44) | DRD3DRD2DRD4 | |
| SCHEMBL3376550 | 0.75 | DRD3 (0.50) | DRD3DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322822-A1 | ARYL PHOSPHOROUS OXIDE COMPOUNDS AND USE THEREOF | CHENGDU DI'AO JIUHONG PHARMACEUTICAL FACTORY (CN) | 2023-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322822-A1 | ARYL PHOSPHOROUS OXIDE COMPOUNDS AND USE THEREOF | ALK, EGFR, ROS1 | DRD3 4635/4885DRD2 4532/4885DRD4 4581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.