Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17574447 | 0.79 | MEN1 (0.42) | ALOX15KDM4EMEN1KMT2ANOTUM | |
| SCHEMBL17574446 | 0.79 | MEN1 (0.42) | ALOX15KDM4EMEN1KMT2ANOTUM | |
| SCHEMBL6006397 | 0.78 | LMNA (0.62) | ALOX15KDM4EMEN1KMT2AMAPT | |
| SCHEMBL4828036 | 0.76 | KDM4E (0.50) | KDM4EMEN1KMT2ANOTUMMAPT | |
| SCHEMBL16267064 | 0.76 | ALOX15 (0.74) | ALOX15KDM4EMEN1KMT2AMAPT | |
| SCHEMBL16267065 | 0.76 | ALOX15 (0.74) | ALOX15KDM4EMEN1KMT2AMAPT | |
| SCHEMBL9850503 | 0.75 | PTAFR (0.54) | SLC6A3SLC6A2SLC6A4MEN1KMT2A | |
| SCHEMBL21501988 | 0.74 | MEN1 (0.47) | SLC6A3SLC6A2KDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9850501 | 0.74 | PTAFR (0.53) | SLC6A3SLC6A2SLC6A4MEN1KMT2A | |
| SCHEMBL14432541 | 0.74 | SLC6A2 (0.46) | SLC6A3SLC6A2SLC6A4ALOX15KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160355802-A1 | Compositions and Methods Of Use Thereof For Making Polypeptides With Many Instances Of Nonstandard Amino Acids | YALE UNIVERSITY | 2016-12-08 | — | — | US | disclosed |
| WO-2015120287-A2 | COMPOSITIONS AND METHODS OF USE THEREOF FOR MAKING POLYPEPTIDES WITH MANY INSTANCES OF NONSTANDARD AMINO ACIDS | YALE UNIVERSITY (US) | 2015-08-13 | — | — | WO | disclosed |