SCHEMBL1699367

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15165194	0.92	CYP3A4 (0.39)	CYP3A4PSIP1DHODHMEN1KMT2A
	SCHEMBL1699777	0.91	CYP3A4 (0.50)	CYP3A4PSIP1PTGDR2
	SCHEMBL10271610	0.90	CYP3A4 (0.49)	CYP3A4PSIP1PTGDR2
	SCHEMBL1699335	0.89	PSIP1 (0.50)	CYP3A4PSIP1DHODHPTGDR2
	SCHEMBL1699531	0.89	CYP3A4 (0.37)	CYP3A4PSIP1DHODHMEN1KMT2A
	SCHEMBL15099647	0.89	CYP3A4 (0.37)	CYP3A4PSIP1DHODHMEN1KMT2A
	SCHEMBL10271607	0.88	CYP3A4 (0.47)	CYP3A4PSIP1PTGDR2
	SCHEMBL10271802	0.87	CYP3A4 (0.46)	CYP3A4PSIP1PTGDR2
	SCHEMBL18892119	0.87	CYP3A4 (0.38)	CYP3A4PSIP1
	SCHEMBL1699278	0.86	CYP3A4 (0.49)	CYP3A4PSIP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.