SCHEMBL16994154

SCHEMBL16994154

COC(C)(C)C(=O)c1cccc(C(=O)C(C)(C)OC)c1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.46
CES1 P23141 2/20 0.44
CES2 O00748 1/20 0.42
NPSR1 Q6W5P4 1/20 0.41
ATM Q13315 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
SRC P12931 1/20 0.40
PARP1 P09874 1/20 0.40
TSHR P16473 1/20 0.39
POLB P06746 1/20 0.39
RAB9A P51151 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39
MEN1 O00255 1/20 0.38
LMNA P02545 1/20 0.38
KMT2A Q03164 1/20 0.38
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10090157 0.85 CES1 (0.60) CES1CES2TDP1L3MBTL1SRC
SCHEMBL15197895 0.84 CYP4F2 (0.46) TSHRRAB9ARXFP1
SCHEMBL14700260 0.83 MRGPRX4 (0.44) RAB9ARXFP1LMNAALDH1A1
SCHEMBL10948100 0.79 CES1 (0.56) CES1CES2TDP1SRCTSHR
SCHEMBL10944759 0.79 CES1 (0.53) CES1ATMTDP1L3MBTL1SRC
SCHEMBL10031819 0.78 ACHE (0.52) ACHENPSR1ATMTDP1L3MBTL1
SCHEMBL10944841 0.76 TTR (0.56) ATML3MBTL1POLBRAB9AMEN1
SCHEMBL12013627 0.76 ACHE (0.50) ACHENPSR1ATMTDP1L3MBTL1
SCHEMBL14700280 0.75 MRGPRX4 (0.56) L3MBTL1RAB9ARXFP1LMNAALDH1A1
SCHEMBL10712634 0.75 TDP1 (0.52) CES1CES2NPSR1ATMTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9107307-B2 Resin composition for printed circuit board, insulating film, prepreg, and printed circuit board SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) 2015-08-11 US disclosed