SCHEMBL1699441

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1701370	0.83	CSF1R (0.41)	CSF1RXBP1SMN1; SMN2MAPTCYP1A2
	SCHEMBL10272102	0.82	PTGDR2 (0.37)	PTGDR2XBP1SMN1; SMN2POLBKMT2A
	SCHEMBL15165287	0.82	CSF1R (0.40)	CSF1RXBP1SMN1; SMN2MAPTCYP1A2
	SCHEMBL1699614	0.80	LMNA (0.36)	CSF1RXBP1POLBKMT2AMEN1
	SCHEMBL10271593	0.79	CYP3A4 (0.38)	PTGDR2XBP1SMN1; SMN2POLBKMT2A
	SCHEMBL18860757	0.79	PTGDR2 (0.37)	PTGDR2XBP1SMN1; SMN2POLBKMT2A
	SCHEMBL18860758	0.79	PTGDR2 (0.37)	PTGDR2XBP1SMN1; SMN2POLBKMT2A
	SCHEMBL1699571	0.78	PTGDR2 (0.37)	PTGDR2CYP3A4ADORA1DHODHHSD11B1
	SCHEMBL10272118	0.77	PTGDR2 (0.36)	PTGDR2CSF1RXBP1SMN1; SMN2KMT2A
	SCHEMBL1699534	0.77	CSF1R (0.47)	PTGDR2CSF1RXBP1SMN1; SMN2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.