Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 5/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 5/20 | 0.46 |
| ▸ | VHL | P40337 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 3/20 | 0.46 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | CPA2 | P48052 | 1/20 | 0.44 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL403446 | 0.91 | SLC6A2 (0.50) | SLC6A2MMEMMEL1ITGB1ITGA4 | |
| SCHEMBL6543907 | 0.79 | CPA1 (0.51) | ITGB1ITGA4ACECPA1CPA2 | |
| SCHEMBL5037359 | 0.79 | GYS1 (0.56) | MMEMMEL1ACE | |
| SCHEMBL5037364 | 0.79 | GYS1 (0.56) | MMEMMEL1ACE | |
| SCHEMBL6353403 | 0.78 | ACE (0.50) | ACEELANE | |
| SCHEMBL20707067 | 0.78 | CYP3A4 (0.52) | ITGB1ITGA4ACECYP3A4CYP2C9 | |
| SCHEMBL6354335 | 0.76 | PSMB9 (0.51) | ITGB1ITGA4 | |
| SCHEMBL14723759 | 0.76 | ALDH1A1 (0.59) | ITGB1ITGA4CYP2C9CYP2C19 | |
| SCHEMBL10956149 | 0.76 | F2 (0.48) | ITGB1ITGA4ACECPA1CPA2 | |
| SCHEMBL5040451 | 0.75 | GYS1 (0.52) | MMEMMEL1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2295402-B1 | Antibacterial agents | UNIV WASHINGTON (US) | 2015-08-12 | — | — | EP | disclosed |