Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 5/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PLG | P00747 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.30 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13806979 | 0.82 | BRD4 (0.46) | BRD4PTGS2FFAR4F2PLG | |
| SCHEMBL23369374 | 0.69 | BRD4 (0.37) | BRD4PTGS2FFAR4CAMKK2NCOA1 | |
| SCHEMBL4262930 | 0.67 | CYP1A2 (0.46) | — | |
| SCHEMBL4276677 | 0.64 | MCL1 (0.44) | — | |
| SCHEMBL8664846 | 0.61 | CYP1A2 (0.49) | NCOA1NCOA3 | |
| SCHEMBL4266240 | 0.59 | CLK4 (0.43) | — | |
| SCHEMBL12907412 | 0.58 | BRD4 (0.46) | BRD4PTGS2FFAR4CAMKK2SCN9A | |
| SCHEMBL12907425 | 0.58 | CHEK1 (0.48) | BRD4PTGS2FFAR4CAMKK2SCN9A | |
| SCHEMBL5477798 | 0.58 | FYN (0.53) | BRD4PTGS2FFAR4NCOA1NCOA3 | |
| SCHEMBL13806958 | 0.58 | STK10 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1999226-B1 | NEW MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-08-12 | — | — | EP | disclosed |