Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.37 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL132012 | 0.81 | BRD4 (0.51) | BRD4FFAR4CAMKK2PTGS2TTR | |
| SCHEMBL19506965 | 0.72 | FFAR4 (0.46) | BRD4FFAR4CAMKK2PTGS2GAA | |
| SCHEMBL22699489 | 0.72 | FFAR4 (0.48) | BRD4FFAR4CAMKK2PTGS2NCOA1 | |
| SCHEMBL12551362 | 0.70 | HPGD (0.46) | BRD4FFAR4CAMKK2PTGS2NCOA1 | |
| SCHEMBL16995360 | 0.69 | BRD4 (0.36) | BRD4FFAR4CAMKK2PTGS2NCOA1 | |
| SCHEMBL20075862 | 0.68 | FFAR4 (0.47) | FFAR4CAMKK2NCOA1NCOA3 | |
| SCHEMBL12187058 | 0.66 | GABRA1 (0.33) | — | |
| SCHEMBL9483097 | 0.66 | NCOA1 (0.62) | FFAR4PTGS2GAANCOA1NCOA3 | |
| Bicarbonate SCHEMBL28250947 | 0.65 | NCOA1 (0.65) | BRD4FFAR4CAMKK2PTGS2GAA | |
| SCHEMBL28092935 | 0.65 | NCOA1 (0.60) | FFAR4PTGS2GAANCOA1NCOA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3658564-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2021-05-19 | — | — | EP | disclosed |