Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 6/20 | 0.53 |
| ▸ | LRRK2 | Q5S007 | 14/20 | 0.53 |
| ▸ | TTK | P33981 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL380932 | 0.90 | PTK2 (0.52) | PTK2LRRK2TTK | |
| SCHEMBL12119496 | 0.83 | LRRK2 (0.48) | PTK2LRRK2TTK | |
| SCHEMBL12745482 | 0.82 | LRRK2 (0.51) | PTK2LRRK2TTK | |
| SCHEMBL1467078 | 0.82 | LRRK2 (0.51) | PTK2LRRK2TTK | |
| SCHEMBL1163979 | 0.82 | PTK2 (0.54) | PTK2 | |
| SCHEMBL1466613 | 0.82 | LRRK2 (0.51) | PTK2LRRK2TTK | |
| SCHEMBL12745485 | 0.82 | LRRK2 (0.51) | PTK2LRRK2TTK | |
| SCHEMBL16995441 | 0.78 | LRRK2 (0.70) | PTK2LRRK2TTK | |
| SCHEMBL14331596 | 0.78 | PTK2 (0.53) | PTK2LRRK2TTK | |
| SCHEMBL10205847 | 0.78 | PTK2 (0.53) | PTK2LRRK2TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408752-B1 | SUBSTITUTED PYRIMIDINES FOR THE TREATMENT OF CANCER | BOEHRINGER INGELHEIM INT (DE) | 2015-08-12 | — | — | EP | disclosed |