SCHEMBL1699544

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15165174	0.92	CYP3A4 (0.40)	CYP3A4PSIP1KDM4ECA1CA2
	SCHEMBL1699452	0.91	CYP3A4 (0.50)	CYP3A4PSIP1DHODHPLA2G2A
	SCHEMBL1701408	0.89	CYP3A4 (0.49)	CYP3A4PSIP1DHODH
	SCHEMBL1699300	0.89	CYP3A4 (0.39)	CYP3A4KDM4ECA1CA2CYP19A1
	SCHEMBL1699396	0.89	PSIP1 (0.50)	CYP3A4PSIP1DHODH
	SCHEMBL1699307	0.88	CYP3A4 (0.45)	CYP3A4PSIP1DHODH
	SCHEMBL1699287	0.87	CYP3A4 (0.47)	CYP3A4PSIP1DHODH
	SCHEMBL18891830	0.87	PSIP1 (0.51)	CYP3A4PSIP1DHODHMAPT
	SCHEMBL1699246	0.85	CYP3A4 (0.49)	CYP3A4PSIP1MAPTTP53THRB
	SCHEMBL1699278	0.85	CYP3A4 (0.49)	CYP3A4PSIP1MAPTTP53THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.