Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14337294 | 0.84 | DHODH (0.45) | MAPTLMNAKDM4EHTTDHODH | |
| SCHEMBL14337437 | 0.73 | MAPT (0.50) | MAPTLMNAKDM4EHTTDHODH | |
| SCHEMBL17594927 | 0.67 | POLB (0.44) | MAPTLMNAKDM4EALDH1A1POLB | |
| SCHEMBL16080711 | 0.67 | MAPT (0.74) | MAPTLMNAKDM4EHTTDHODH | |
| SCHEMBL21983921 | 0.66 | MAPT (0.44) | MAPTLMNAKDM4EHTTDHODH | |
| SCHEMBL18859049 | 0.66 | ALOX5 (0.52) | MAPTLMNAKDM4EHTTDHODH | |
| SCHEMBL22560742 | 0.65 | GABRA1 (0.42) | MAPTLMNAKDM4EHTTALDH1A1 | |
| SCHEMBL14337391 | 0.64 | MAPT (0.57) | MAPTLMNAKDM4EHTTDHODH | |
| SCHEMBL10182423 | 0.64 | ALOX5 (0.53) | MAPTLMNAKDM4EHTTDHODH | |
| SCHEMBL22763968 | 0.64 | PTGS2 (0.53) | MAPTLMNAKDM4EHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1243598-B1 | PROCESS FOR THE POLYMERIZATION OF OLEFINS | MITSUI CHEMICALS INC (JP) | 2015-08-12 | — | — | EP | disclosed |