Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | STAT3 | P40763 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18353625 | 0.88 | STAT3 (0.54) | SMN1; SMN2ALDH1A1LMNASTAT3PTGER1 | |
| SCHEMBL16995662 | 0.83 | FNTA (0.65) | SMN1; SMN2ALDH1A1LMNAHTTPTGER1 | |
| SCHEMBL14775776 | 0.74 | PTGER1 (0.55) | SMN1; SMN2ALDH1A1LMNASTAT3PTGER1 | |
| SCHEMBL11887862 | 0.73 | VNN1 (0.51) | SMN1; SMN2ALDH1A1LMNAPOLBMAPT | |
| SCHEMBL16995668 | 0.73 | MAPT (0.49) | ALDH1A1LMNAHTTNPSR1MAPT | |
| SCHEMBL16995676 | 0.73 | HTT (0.57) | SMN1; SMN2ALDH1A1LMNASTAT3HTT | |
| SCHEMBL5699784 | 0.72 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1LMNASTAT3PTGER1 | |
| SCHEMBL16995692 | 0.72 | HTT (0.63) | SMN1; SMN2ALDH1A1LMNASTAT3HTT | |
| SCHEMBL30933759 | 0.71 | SLC6A4 (0.61) | SMN1; SMN2ALDH1A1LMNASTAT3PTGER1 | |
| SCHEMBL18353487 | 0.71 | HDAC1 (0.55) | SMN1; SMN2ALDH1A1SLC6A4SLC6A2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170001968-A1 | AMINOTRIAZOLE- AND AMINOTETRAZOLE-BASED KDM1A INHIBITORS AS EPIGENETIC MODULATORS | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2017-01-05 | — | — | US | disclosed |
| US-20170001968-A1 | AMINOTRIAZOLE- AND AMINOTETRAZOLE-BASED KDM1A INHIBITORS AS EPIGENETIC MODULATORS | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2017-01-05 | — | — | US | disclosed |
| WO-2015120281-A1 | AMINOTRIAZOLE- AND AMINOTETRAZOLE-BASED KDM1A INHIBITORS AS EPIGENETIC MODULATORS | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2015-08-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170001968-A1 | AMINOTRIAZOLE- AND AMINOTETRAZOLE-BASED KDM1A INHIBITORS AS EPIGENETIC MODULATORS | KDM1A, KDM1B, KDM3A | SMN1; SMN2 3412/4885ALDH1A1 198/4885LMNA 3528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.