Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | ABL1 | P00519 | 2/20 | 0.44 |
| ▸ | SRC | P12931 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 3/20 | 0.44 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.44 |
| ▸ | SMOX | Q9NWM0 | 2/20 | 0.44 |
| ▸ | LCK | P06239 | 5/20 | 0.43 |
| ▸ | BTK | Q06187 | 5/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | LYN | P07948 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BMX | P51813 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | EIF2AK1 | Q9BQI3 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18353997 | 0.91 | ABL1 (0.51) | HDAC3HDAC1HDAC2HDAC6ABL1 | |
| SCHEMBL16995685 | 0.83 | HDAC3 (0.51) | HDAC3HDAC1HDAC2HDAC6TP53 | |
| SCHEMBL11887862 | 0.76 | VNN1 (0.51) | HDAC3HDAC1HDAC2HDAC6MAPT | |
| SCHEMBL28357732 | 0.76 | VNN1 (0.49) | HDAC3HDAC1HDAC2HDAC6SMN1; SMN2 | |
| SCHEMBL16995668 | 0.73 | MAPT (0.49) | HDAC1HDAC6MAPTP2RX7EIF2AK1 | |
| Hydrochloric Acid SCHEMBL11551221 | 0.73 | HDAC3 (0.54) | HDAC3HDAC1HDAC2HDAC6LCK | |
| SCHEMBL10906675 | 0.72 | KLKB1 (0.50) | MAPTSMN1; SMN2P2RX7 | |
| SCHEMBL16995669 | 0.72 | L3MBTL1 (0.62) | TP53MAPTSMN1; SMN2P2RX7 | |
| SCHEMBL2633350 | 0.70 | MAOA (0.56) | HDAC3HDAC1HDAC2HDAC6TP53 | |
| SCHEMBL13668646 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170001968-A1 | AMINOTRIAZOLE- AND AMINOTETRAZOLE-BASED KDM1A INHIBITORS AS EPIGENETIC MODULATORS | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2017-01-05 | — | — | US | disclosed |
| WO-2015120281-A1 | AMINOTRIAZOLE- AND AMINOTETRAZOLE-BASED KDM1A INHIBITORS AS EPIGENETIC MODULATORS | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2015-08-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170001968-A1 | AMINOTRIAZOLE- AND AMINOTETRAZOLE-BASED KDM1A INHIBITORS AS EPIGENETIC MODULATORS | KDM1A, KDM1B, KDM3A | HDAC3 127/4885HDAC1 60/4885HDAC2 76/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.