Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10286147 | 0.83 | ALDH1A1 (0.41) | MAPTSMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL526812 | 0.83 | SMN1; SMN2 (0.39) | MAPTSMN1; SMN2TP53MEN1KMT2A | |
| SCHEMBL4173286 | 0.78 | ADRA2A (0.46) | MAPTSMN1; SMN2ADRA2AADRA2BADRA2C | |
| SCHEMBL10286602 | 0.76 | GPR174 (0.35) | MAPTSMN1; SMN2KDM4EALDH1A1POLB | |
| SCHEMBL10286107 | 0.71 | RXFP1 (0.39) | MAPTSMN1; SMN2TP53KDM4EALDH1A1 | |
| SCHEMBL10286502 | 0.71 | ALDH1A1 (0.39) | MAPTSMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL4426496 | 0.70 | GRM5 (0.44) | MAPTSMN1; SMN2TSHRLMNA | |
| SCHEMBL10286613 | 0.70 | ALDH1A1 (0.42) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL10286198 | 0.70 | ALDH1A1 (0.42) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL526092 | 0.70 | SMN1; SMN2 (0.43) | MAPTSMN1; SMN2ADRA2ATP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588456-A1 | NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES | Syngenta Participations AG (CH) | 2013-05-08 | — | — | EP | disclosed |
| WO-2012001040-A1 | NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-05 | — | — | WO | disclosed |