Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 9/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | FLT1 | P17948 | 3/20 | 0.48 |
| ▸ | KDR | P35968 | 3/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.44 |
| ▸ | CLK1 | P49759 | 2/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | CLK3 | P49761 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16997381 | 0.83 | PDE5A (0.59) | PDE5AMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL16997383 | 0.82 | PDE5A (0.56) | PDE5AMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL17001442 | 0.82 | PDE5A (0.55) | PDE5AMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL16997382 | 0.81 | PDE5A (0.57) | PDE5AMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL28088239 | 0.77 | RAB9A (0.59) | MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL17001478 | 0.76 | SMN1; SMN2 (0.60) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7618932 | 0.75 | PDE5A (0.57) | PDE5AMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL7617647 | 0.74 | PDE5A (0.52) | PDE5AMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL7467527 | 0.74 | PDE5A (0.64) | PDE5AMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL20563312 | 0.74 | MAP2K7 (0.53) | PDE5AMEN1ALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9447081-B2 | Substituted pyrimidines as pharmaceuticals and insecticides | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2016-09-20 | — | — | US | disclosed |
| US-9447081-B2 | Substituted pyrimidines as pharmaceuticals and insecticides | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2016-09-20 | — | — | US | disclosed |
| US-20150225378-A1 | HOMOPIPERONY LAMINE COMPOUND AND USE THEREOF | SINOCHEM CORPORATION (CN) | 2015-08-13 | — | — | US | disclosed |
| US-20150225378-A1 | HOMOPIPERONY LAMINE COMPOUND AND USE THEREOF | SINOCHEM CORPORATION (CN) | 2015-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150225378-A1 | HOMOPIPERONY LAMINE COMPOUND AND USE THEREOF | CLPP, LRRK2, MYB | PDE5A 270/4885MEN1 59/4885ALDH1A1 3907/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.