Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2515948 | 0.82 | ALDH1A1 (0.38) | ALDH1A1HTTNPSR1KMT2ASCN1A | |
| SCHEMBL7600486 | 0.80 | ALDH1A1 (0.37) | ALDH1A1HTTNPSR1KMT2ASCN1A | |
| SCHEMBL3704482 | 0.78 | ALDH1A1 (0.42) | ALDH1A1HTTNPSR1KMT2ASCN1A | |
| SCHEMBL11884387 | 0.78 | NPSR1 (0.36) | ALDH1A1HTTNPSR1KMT2ASCN1A | |
| SCHEMBL1650441 | 0.77 | MAPT (0.48) | ALDH1A1HTTNPSR1KMT2ASCN1A | |
| SCHEMBL218350 | 0.77 | ALDH1A1 (0.40) | ALDH1A1HTTNPSR1KMT2A | |
| SCHEMBL3079757 | 0.74 | ALDH1A1 (0.41) | ALDH1A1HTTNPSR1KMT2AMAPT | |
| SCHEMBL28417551 | 0.74 | ALDH1A1 (0.41) | ALDH1A1HTTNPSR1KMT2AMAPT | |
| SCHEMBL216423 | 0.74 | ALDH1A1 (0.43) | ALDH1A1HTTNPSR1KMT2ASCN1A | |
| SCHEMBL8028307 | 0.74 | ALDH1A1 (0.33) | ALDH1A1HTTNPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119816487-A | FC conjugates comprising CD73 inhibitors and uses thereof | 奇达拉治疗公司 | 2025-04-11 | — | — | CN | disclosed |
| CN-119053336-A | Compositions and methods for treating autoimmune disorders | 密执安大学评议会 | 2024-11-29 | — | — | CN | disclosed |
| CN-114302741-A | Compositions and methods for treating autoimmune disorders | 密执安大学评议会 | 2022-04-08 | — | — | CN | disclosed |
| US-9511120-B2 | Use of the angiotensin-(1-9) peptide or derivatives thereof, use of vectors overexpressing the ACE2 enzyme that produces angiotensin-(1-9) for preparing medicaments useful for preventing, reverting, inhibiting and/or reducing hypertension and/or inducing vasodilation | PONTIFICA UNIVERSIDAD CATÓLICA DE CHILE (CL) | 2016-12-06 | — | — | US | disclosed |
| US-9132164-B2 | Pharmaceutical compositions comprising angiotensin-(1-9), derivatives thereof, or a vector expressing ACE2, useful for treating cardiovascular, pulmonary, cerebral, and/or renal remodeling | PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE (CL) | 2015-09-15 | — | — | US | disclosed |
| US-20150190472-A1 | USE OF THE ANGIOTENSIN-(1-9) PEPTIDE OR DERIVATIVES THEREOF, USE OF VECTORS OVEREXPRESSING THE ACE2 ENZYME THAT PRODUCES ANGIOTENSIN-(1-9) FOR PREPARING MEDICAMENTS USEFUL FOR PREVENTING, REVERTING, INHIBITING AND/OR REDUCING HYPERTENSION AND/OR INDUCING VASODILATION | PONTIFICA UNIVERSIDAD CATOLICA DE CHILE (CL) | 2015-07-09 | — | — | US | disclosed |
| EP-2377544-B1 | PHARMACEUTICAL COMPOSITION CONTAINING ANGIOTENSIN-(1-9) FOR CARDIOVASCULAR, PULMONARY AND/OR CEREBRAL TREATMENT | PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE (CL) | 2014-10-22 | — | — | EP | disclosed |
| CN-101784522-B | Proton acceptor iminium/carbocationic coupling agents | LUXEMBOURG BIOTECHNOLOGIES LTD | 2014-05-28 | — | — | CN | disclosed |
| US-20120172301-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING ANGIOTENSIN-(1-9), DERIVATIVES THEREOF, OR A VECTOR EXPRESSING ACE2, USEFUL FOR TREATING CARDIOVASCULAR, PULMONARY, CEREBRAL, AND/OR RENAL REMODELING | PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE (CL) | 2012-07-05 | — | — | US | disclosed |
| EP-2377544-A2 | PHARMACEUTICAL COMPOSITION CONTAINING ANGIOTENSIN-(1-9) FOR CARDIOVASCULAR, PULMONARY AND/OR CEREBRAL TREATMENT | Pontificia Universidad Católica De Chile (CL) | 2011-10-19 | — | — | EP | disclosed |
| WO-2011005980-A1 | NOVEL HETEROBIFUNCTIONAL POLYETHYLENE GLYCOL REAGENTS, THEIR PREPARATION AND USES THEREOF | INTRADIGM CORPORATION (US) | 2011-01-13 | — | — | WO | disclosed |
| CN-101784522-A | Proton acceptor iminium/carbocationic coupling agents | LUXEMBOURG BIOTECHNOLOGIES LTD | 2010-07-21 | — | — | CN | disclosed |
| CN-1973041-A | Therapeutic molecules and methods of producing and/or selecting the same | INST MEDICAL W & E HALL (AU) | 2007-05-30 | — | — | CN | disclosed |
| CN-1247613-C | Novel omega-conotoxin peptides | UNIV QUEENSLAND (AU) | 2006-03-29 | — | — | CN | disclosed |