Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645202 | 0.91 | GLA (0.40) | ALDH1A1NPSR1HTTGLAL3MBTL1 | |
| Isothiocyanate SCHEMBL27733961 | 0.89 | ALDH1A1 (0.40) | ALDH1A1NPSR1HTTGLAL3MBTL1 | |
| SCHEMBL9951753 | 0.88 | NPSR1 (0.38) | ALDH1A1NPSR1HTTGLAL3MBTL1 | |
| SCHEMBL5188438 | 0.86 | NPSR1 (0.39) | ALDH1A1NPSR1HTTGLAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL29184967 | 0.84 | NPSR1 (0.38) | ALDH1A1NPSR1HTTGLAL3MBTL1 | |
| SCHEMBL2515948 | 0.82 | ALDH1A1 (0.38) | ALDH1A1NPSR1HTTGLAKMT2A | |
| SCHEMBL17586310 | 0.81 | — | — | |
| SCHEMBL7485102 | 0.81 | GLA (0.38) | ALDH1A1NPSR1HTTGLAL3MBTL1 | |
| SCHEMBL7600486 | 0.80 | ALDH1A1 (0.37) | ALDH1A1NPSR1HTTKMT2ASCN1A | |
| SCHEMBL30706809 | 0.80 | GLA (0.37) | ALDH1A1NPSR1HTTGLAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115433212-A | Biphenyl compound as immunomodulator and preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2022-12-06 | — | — | CN | claimed |
| CN-114698376-A | Biphenyl compound as immunomodulator, and preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2022-07-01 | — | — | CN | claimed |
| US-12577260-B2 | Biphenyl compound as immunomodulator, preparation method therefor and application thereof | SHENZHEN CHIPSCREEN BIOSCIENCES CO., LTD. (CN) | 2026-03-17 | — | — | US | disclosed |
| US-20250325660-A1 | IMMUNOMODULATOR COMPOUNDS AND METHODS OF USE | INCYTE CORP (US) | 2025-10-23 | — | — | US | disclosed |
| US-20250135059-A1 | COMPOSITIONS COMPRISING FRAGRANCE MATERIALS | THE PROCTER & GAMBLE COMPANY | 2025-05-01 | — | — | US | disclosed |
| CN-118908978-A | Tetrahydro-imidazo [4,5-c ] pyridine derivatives as PD-L1 immunomodulators | 因赛特公司 | 2024-11-08 | — | — | CN | disclosed |
| CN-115677689-B | Polysubstituted benzene PD-L1 inhibitor, composition and application thereof | 杭州和正医药有限公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-112752756-B | Tetrahydro-imidazo [4,5-c ] pyridine derivatives as PD-L1 immunomodulators | 因赛特公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-115232125-B | Polysubstituted benzene immunomodulatory compounds, composition and application thereof | 杭州和正医药有限公司 | 2024-06-18 | — | — | CN | disclosed |
| US-20240190855-A1 | CDK INHIBITORS AND METHODS OF USE THEREOF | RELAY THERAPEUTICS, INC. | 2024-06-13 | — | — | US | disclosed |
| CN-115175734-B | Pyrido [3,2-D ] pyrimidine compounds as immunomodulators | 因赛特公司 | 2024-04-19 | — | — | CN | disclosed |
| US-9057949-B2 | Patterning process, resist composition, polymer, and polymerizable ester compound | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2015-06-16 | — | — | US | disclosed |
| US-20130157194-A1 | PATTERNING PROCESS, RESIST COMPOSITION, POLYMER, AND POLYMERIZABLE ESTER COMPOUND | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-06-20 | — | — | US | disclosed |
| EP-2460785-A1 | METHOD FOR PRODUCING ESTER COMPOUND | Hitachi Chemical Company, Ltd. (JP) | 2012-06-06 | — | — | EP | disclosed |
| CN-102471219-A | Method for producing ester compound | HITACHI CHEMICAL CO LTD | 2012-05-23 | — | — | CN | disclosed |
| US-20120123146-A1 | METHOD FOR PRODUCING ESTER COMPOUND | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2012-05-17 | — | — | US | disclosed |
| EP-1261586-B1 | CYCLOPROPYL-FUSED PYRROLIDINE-BASED INHIBITORS OF DIPEPTIDYL PEPTIDASE IV, PROCESSES FOR THEIR PREPARATION, AND THEIR USE | BRISTOL MYERS SQUIBB CO (US) | 2008-05-21 | — | — | EP | disclosed |
| CN-1698601-A | Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl iv, processes for their preparation, and their use | BRISTOL MYERS SQUIBB CO (US) | 2005-11-23 | — | — | CN | disclosed |
| CN-1213028-C | Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV, methods for their preparation and uses thereof | BRISTOL MYERS SQUIBB CO (US) | 2005-08-03 | — | — | CN | disclosed |
| CN-1427826-A | Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV, methods for their preparation and uses thereof | BRISTOL MYERS SQUIBB CO (US) | 2003-07-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250325660-A1 | IMMUNOMODULATOR COMPOUNDS AND METHODS OF USE | CD274, PDCD1LG2, PDCD1 | ALDH1A1 1759/4885NPSR1 414/4885HTT 3206/4885 |
| US-12577260-B2 | Biphenyl compound as immunomodulator, preparation method therefor and application thereof | CCR1, CCR6, CCL11 | ALDH1A1 294/4885NPSR1 1431/4885HTT 4517/4885 |
| US-20240190855-A1 | CDK INHIBITORS AND METHODS OF USE THEREOF | CDK3, CDK8, CDK6 | ALDH1A1 3717/4885NPSR1 4649/4885HTT 3611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.