Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | PGR | P06401 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16999348 | 1.00 | LMNA (0.59) | LMNAMAPTTDP1PGRMAPK1 | |
| SCHEMBL16999349 | 0.97 | LMNA (0.62) | LMNAMAPTTDP1PGRMAPK1 | |
| Coenzyme Q1 SCHEMBL1129498 | 0.84 | LMNA (0.73) | LMNAMAPTTDP1PGRMAPK1 | |
| SCHEMBL4318927 | 0.78 | LMNA (0.61) | LMNAMAPTTDP1PGRMAPK1 | |
| SCHEMBL2625087 | 0.77 | LMNA (0.68) | LMNAMAPTTDP1PGRMAPK1 | |
| SCHEMBL14407307 | 0.76 | LMNA (0.62) | LMNAMAPTTDP1PGRMAPK1 | |
| SCHEMBL14407313 | 0.76 | LMNA (0.62) | LMNAMAPTTDP1PGRMAPK1 | |
| Coenzyme Q2 SCHEMBL623496 | 0.75 | LMNA (0.97) | LMNAMAPTPGRMAPK1PDE3A | |
| Coenzyme Q2 SCHEMBL1506676 | 0.75 | LMNA (0.97) | LMNAMAPTPGRMAPK1PDE3A | |
| SCHEMBL18715960 | 0.75 | LMNA (0.72) | LMNAMAPTTDP1PGRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150224066-A1 | ANTIMICROBIAL COMPOSITIONS AND METHODS OF USE | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2015-08-13 | — | — | US | disclosed |