Coenzyme Q2

Coenzyme Q2

SCHEMBL1506676

COC1=C(OC)C(=O)C(CC=C(C)CCC=C(C)C)=C(C)C1=O

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.97
▸ MAOB P27338 2/20 0.68
▸ PTGS1 P23219 3/20 0.64
▸ PGR P06401 1/20 0.64
▸ HTR1A P08908 1/20 0.64
▸ ADORA3 P0DMS8 1/20 0.64
▸ MAPT P10636 1/20 0.64
▸ PDE4A P27815 1/20 0.64
▸ MAPK1 P28482 1/20 0.64
▸ DRD3 P35462 1/20 0.64
▸ SNCA P37840 1/20 0.64
▸ PDE3A Q14432 1/20 0.64
▸ ALOX5 P09917 9/20 0.61
▸ ALOX15 P16050 1/20 0.45
▸ APP P05067 3/20 0.44
▸ BACE1 P56817 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Coenzyme Q2 SCHEMBL623496 1.00 LMNA (0.97) LMNAMAOBPTGS1PGRHTR1A
SCHEMBL5530210 0.99 LMNA (1.00) LMNAMAOBPTGS1PGRHTR1A
Ubidecarenone SCHEMBL19858 0.99 LMNA (1.00) LMNAMAOBPTGS1PGRHTR1A
Coenzyme Q4 SCHEMBL6279406 0.99 LMNA (1.00) LMNAMAOBPTGS1PGRHTR1A
Ubidecarenone SCHEMBL13026488 0.99 LMNA (1.00) LMNAMAOBPTGS1PGRHTR1A
SCHEMBL16393869 0.99 LMNA (1.00) LMNAMAOBPTGS1PGRHTR1A
SCHEMBL9975753 0.99 LMNA (1.00) LMNAMAOBPTGS1PGRHTR1A
Ubidecarenone SCHEMBL11901691 0.99 LMNA (1.00) LMNAMAOBPTGS1PGRHTR1A
Coenzyme Q4 SCHEMBL6279408 0.99 LMNA (1.00) LMNAMAOBPTGS1PGRHTR1A
SCHEMBL29402769 0.99 LMNA (1.00) LMNAMAOBPTGS1PGRHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110059898-A1 PRO-OXIDANT ANTI-CANCER COMPOUNDS CANCURE LIMITED (AU) 2011-03-10 — — US claimed
EP-2063884-A1 PRO-OXIDANT ANTI-CANCER COMPOUNDS Ralph, John Stephen (AU) 2009-06-03 — — EP claimed
WO-2008031171-A1 PRO-OXIDANT ANTI-CANCER COMPOUNDS UNIV GRIFFITH (AU) 2008-03-20 — — WO claimed
US-11945862-B2 Compositions and methods for antibody production IMMUNOGEN, INC. (US) 2024-04-02 — — US disclosed
US-20220204650-A1 SYSTEMS AND METHODS FOR IMMOBILIZING A TARGET PROTEIN UNIVERSITY OF SOUTH FLORIDA (US) 2022-06-30 — — US disclosed
US-20210130457-A1 COMPOSITIONS AND METHODS FOR ANTIBODY PRODUCTION IMMUNOGEN, INC 2021-05-06 — — US disclosed
US-10913795-B2 Compositions and methods for antibody production IMMUNOGEN, INC. (US) 2021-02-09 — — US disclosed
US-20190119374-A1 COMPOSITIONS AND METHODS FOR ANTIBODY PRODUCTION IMMUNOGEN, INC. 2019-04-25 — — US disclosed
US-20170002393-A1 COMPOSITIONS AND METHODS FOR ANTIBODY PRODUCTION IMMUNOGEN, INC. (US) 2017-01-05 — — US disclosed
EP-3077522-A1 COMPOSITIONS AND METHODS FOR ANTIBODY PRODUCTION Immunogen, Inc. (US) 2016-10-12 — — EP disclosed
WO-2015085003-A1 COMPOSITIONS AND METHODS FOR ANTIBODY PRODUCTION IMMUNOGEN, INC. (US) 2015-06-11 — — WO disclosed
EP-2063884-B1 PRO-OXIDANT ANTI-CANCER COMPOUNDS RALPH STEPHEN JOHN (AU) 2014-08-13 — — EP disclosed
US-8410056-B2 Pro-oxidant anti-cancer compounds CANCURE LIMITED (AU) 2013-04-02 — — US disclosed
US-20110059898-A1 PRO-OXIDANT ANTI-CANCER COMPOUNDS CANCURE LIMITED (AU) 2011-03-10 — — US disclosed
EP-2063884-A1 PRO-OXIDANT ANTI-CANCER COMPOUNDS Ralph, John Stephen (AU) 2009-06-03 — — EP disclosed
WO-2008031171-A1 PRO-OXIDANT ANTI-CANCER COMPOUNDS UNIV GRIFFITH (AU) 2008-03-20 — — WO disclosed
US-6635802-B1 Culturing mammalian cell population in serum starvation media containing apoptosis inhibitor to increase number of cells at G0/G1 stage of cell cycle within cell population, increasing number of nuclear transfer competent cells THE TEXAS A&M UNIVERSITY SYSTEM 2003-10-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190119374-A1 COMPOSITIONS AND METHODS FOR ANTIBODY PRODUCTION TXNRD1, P4HB, CYBB LMNA 3496/4885MAOB 2560/4885PTGS1 1016/4885
US-11945862-B2 Compositions and methods for antibody production TXNRD1, P4HB, CYBB LMNA 3496/4885MAOB 2560/4885PTGS1 1016/4885
US-10913795-B2 Compositions and methods for antibody production TXNRD1, P4HB, CYBB LMNA 3496/4885MAOB 2560/4885PTGS1 1016/4885
US-20210130457-A1 COMPOSITIONS AND METHODS FOR ANTIBODY PRODUCTION TXNRD1, P4HB, CYBB LMNA 3496/4885MAOB 2560/4885PTGS1 1016/4885
US-20110059898-A1 PRO-OXIDANT ANTI-CANCER COMPOUNDS PRDX5, MT-ND2, UQCRC2 LMNA 550/4885MAOB 2940/4885PTGS1 347/4885
US-20170002393-A1 COMPOSITIONS AND METHODS FOR ANTIBODY PRODUCTION TXNRD1, P4HB, CYBB LMNA 3496/4885MAOB 2560/4885PTGS1 1016/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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