SCHEMBL16999963

SCHEMBL16999963

C/C(=N\c1c(C(C)C)cc(C)cc1C(C)C)c1cccc(/C(C)=N/c2c(C(C)C)cc(Cl)cc2C(C)C)n1

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.37
GABRB1 P18505 1/20 0.37
LMNA P02545 1/20 0.34
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
NPY5R Q15761 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14820625 0.94 GABRA1 (0.41) GABRA1GABRB1LMNA
SCHEMBL6910795 0.93 GABRA1 (0.33) GABRA1GABRB1LMNAMEN1KMT2A
SCHEMBL5589024 0.93 GABRA1 (0.33) GABRA1GABRB1LMNAMEN1KMT2A
SCHEMBL5590045 0.92 GABRA1 (0.33) GABRA1GABRB1LMNAMEN1KMT2A
Hydrochloric Acid SCHEMBL7178317 0.90 GABRA1 (0.32) GABRA1GABRB1LMNAMEN1KMT2A
Hydrochloric Acid SCHEMBL7176822 0.90 GABRA1 (0.32) GABRA1GABRB1LMNAMEN1KMT2A
Hydrochloric Acid SCHEMBL7174370 0.90 GABRA1 (0.32) GABRA1GABRB1LMNAMEN1KMT2A
Hydrochloric Acid SCHEMBL7176931 0.90 GABRA1 (0.32) GABRA1GABRB1LMNAMEN1KMT2A
Hydrochloric Acid SCHEMBL7180672 0.90 GABRA1 (0.32) GABRA1GABRB1LMNAMEN1KMT2A
Hydrochloric Acid SCHEMBL7175518 0.90 GABRA1 (0.32) GABRA1GABRB1LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150224490-A1 Hydrosilylation Catalysts Made With Terdentate Nitrogen Ligands And Compositions Containing The Catalysts DOW CORNING (US) 2015-08-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150224490-A1 Hydrosilylation Catalysts Made With Terdentate Nitrogen Ligands And Compositions Containing The Catalysts HIRA, TPR, TST GABRA1 1885/4885GABRB1 2895/4885LMNA 1734/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.