SCHEMBL1700153

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1700045	0.85	CA2 (0.42)	FFAR2LMNANPC1HTTRAB9A
	SCHEMBL1808963	0.84	BCL2L1 (0.38)	SLC6A4CNR2FFAR2SLC6A2LMNA
	SCHEMBL1700396	0.83	ALDH1A1 (0.42)	FFAR2LMNANPC1HTTRAB9A
	SCHEMBL1700343	0.82	PTGS1 (0.43)	SLC6A4SCN1ASCN8AFFAR2SLC6A2
	SCHEMBL523814	0.80	HTT (0.52)	LMNANPC1HTTRAB9ASMN1; SMN2
	SCHEMBL1700139	0.79	FFAR2 (0.35)	FFAR2LMNANPC1HTTRAB9A
	SCHEMBL2483132	0.77	HSP90AA1 (0.34)	FFAR2LMNANPC1HTTRAB9A
	SCHEMBL1700199	0.77	HTT (0.47)	LMNANPC1HTTRAB9ASMN1; SMN2
	SCHEMBL16037787	0.76	HTT (0.53)	LMNANPC1HTTRAB9ASMN1; SMN2
	SCHEMBL2482923	0.76	CA2 (0.50)	FFAR2LMNANPC1RAB9APTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.