Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 5/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 5/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 5/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1893357 | 0.87 | ALDH1A1 (0.44) | ADRA2AADRA2BADRA2CAOC3ALDH1A1 | |
| SCHEMBL753789 | 0.79 | TDP1 (0.38) | AOC3ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28337647 | 0.75 | ALDH1A1 (0.46) | ADRA2AADRA2BADRA2CALDH1A1CYP1A2 | |
| SCHEMBL28337644 | 0.75 | ALDH1A1 (0.46) | ADRA2AADRA2BADRA2CALDH1A1CYP1A2 | |
| SCHEMBL7299447 | 0.75 | ALDH1A1 (0.46) | ADRA2AADRA2BADRA2CALDH1A1CYP1A2 | |
| SCHEMBL10420202 | 0.73 | ALDH1A1 (0.44) | ADRA2AADRA2BADRA2CALDH1A1CYP1A2 | |
| SCHEMBL7294198 | 0.73 | EPHX1 (0.55) | ALDH1A1CYP2C9SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL16974437 | 0.71 | ADRA2A (0.61) | ADRA2AADRA2BADRA2CAOC3ALDH1A1 | |
| SCHEMBL2524557 | 0.71 | ALDH1A1 (0.54) | ADRA2AADRA2BADRA2CAOC3ALDH1A1 | |
| SCHEMBL31127390 | 0.71 | ALDH1A1 (0.54) | ADRA2AADRA2BADRA2CAOC3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2576702-A1 | USE OF SURFACE-MODIFIED EFFECT PIGMENTS IN A SOLVENT-FREE COATING AGENT, SOLVENT-FREE COATING AGENT AND COATED OBJECT | Eckart GmbH (DE) | 2013-04-10 | — | — | EP | disclosed |
| WO-2011147892-A1 | USE OF SURFACE-MODIFIED EFFECT PIGMENTS IN A SOLVENT-FREE COATING AGENT, SOLVENT-FREE COATING AGENT AND COATED OBJECT | ECKART GMBH (DE) | 2011-12-01 | — | — | WO | disclosed |