SCHEMBL1893357

SCHEMBL1893357

c1ccc2c(C(OC(c3cccc4ccccc34)C3CO3)C3CO3)cccc2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
AOC3 Q16853 1/20 0.36
SSTR4 P31391 3/20 0.35
ACP3 P15309 1/20 0.35
ADRA2A P08913 3/20 0.34
ADRA2B P18089 3/20 0.34
ADRA2C P18825 3/20 0.34
NPC1 O15118 1/20 0.34
MAPT P10636 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
ADRA1D P25100 1/20 0.33
ADRA1A P35348 1/20 0.33
ADRA1B P35368 1/20 0.33
SLC6A4 P31645 1/20 0.33
CASR P41180 2/20 0.33
METAP2 P50579 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1700175 0.87 ADRA2A (0.43) ALDH1A1CYP1A2CYP2C9CYP2C19AOC3
SCHEMBL753789 0.82 TDP1 (0.38) ALDH1A1CYP1A2CYP2C9CYP2C19AOC3
SCHEMBL8904408 0.82 ALDH1A1 (0.34) ALDH1A1CYP1A2
SCHEMBL8847185 0.81 POLB (0.39) ALDH1A1CYP1A2CYP2C9CYP2C19NPC1
SCHEMBL8847091 0.80 TRPM4 (0.35) ALDH1A1MAPT
SCHEMBL28337647 0.77 ALDH1A1 (0.46) ALDH1A1CYP1A2CYP2C9CYP2C19SSTR4
SCHEMBL7299447 0.77 ALDH1A1 (0.46) ALDH1A1CYP1A2CYP2C9CYP2C19SSTR4
SCHEMBL28337644 0.77 ALDH1A1 (0.46) ALDH1A1CYP1A2CYP2C9CYP2C19SSTR4
SCHEMBL8847377 0.77 CYP1A2 (0.42) CYP1A2
SCHEMBL10420202 0.76 ALDH1A1 (0.44) ALDH1A1CYP1A2CYP2C9CYP2C19SSTR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12590181-B2 Hydrophobically-modified associative thickener polymers process for the preparation and uses thereof HERCULES LLC (US) 2026-03-31 US claimed
EP-4192923-B1 HYDROPHOBICALLY-MODIFIED ASSOCIATIVE THICKENER POLYMERS PROCESS FOR THE PREPARATION AND USES THEREOF HERCULES LLC (US) 2025-10-29 EP claimed
US-20230323138-A1 HYDROPHOBICALLY-MODIFIED ASSOCIATIVE THICKENER POLYMERS PROCESS FOR THE PREPARATION AND USES THEREOF HERCULES LLC (US) 2023-10-12 US claimed
US-20230257522-A1 HYDROPHOBICALLY-MODIFIED ASSOCIATIVE THICKENER POLYMERS PROCESS FOR THE PREPARATION AND USES THEREOF HERCULES LLC (US) 2023-08-17 US claimed
EP-4192923-A1 HYDROPHOBICALLY-MODIFIED ASSOCIATIVE THICKENER POLYMERS PROCESS FOR THE PREPARATION AND USES THEREOF Hercules LLC (US) 2023-06-14 EP claimed
EP-4192922-A1 HYDROPHOBICALLY-MODIFIED ASSOCIATIVE THICKENER POLYMERS PROCESS FOR THE PREPARATION AND USES THEREOF Hercules LLC (US) 2023-06-14 EP claimed
EP-0605937-B1 Antistatic resin composition DAISO CO LTD (JP) 1997-06-11 EP claimed
US-5556916-A ACRYLONITRILE-BUTADIENE-STYRENE TERPOLYMER WITH POLYOXYETHYLENE GLYCOL POLYMER OR COPOLYMER ON RUBBER SUBSTRATE DAISO CO. LTD. (JP) 1996-09-17 US claimed
JP-5148404-A None JP disclosed
JP-2164897-A None JP disclosed
US-12624164-B2 Synthetic thickeners incorporating non-reactive diluents HERCULES LLC (US) 2026-05-12 US disclosed
US-12590181-B2 Hydrophobically-modified associative thickener polymers process for the preparation and uses thereof HERCULES LLC (US) 2026-03-31 US disclosed
EP-4192923-B1 HYDROPHOBICALLY-MODIFIED ASSOCIATIVE THICKENER POLYMERS PROCESS FOR THE PREPARATION AND USES THEREOF HERCULES LLC (US) 2025-10-29 EP disclosed
EP-3823904-B1 WATER SOLUBLE OR DISPERSIBLE COMPOSITION HERCULES LLC (US) 2025-10-29 EP disclosed
EP-0170474-A2 Water-borne coating compositions containing metallic pigment having reduced tendency to gas generation on storage IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-02-05 EP disclosed
US-4450173-A BRIEF ACTING B-ADRENERGIC BLOCKING AGENTS; BIOLOGICAL INJECTIONS; ANTIARRYHYTHMIA AGENTS AMERICAN HOSPITAL SUPPLY CORPORATION (US) 1984-05-22 US disclosed
EP-0065963-A4 COMPOUNDS AND METHOD FOR TREATMENT OR PROPHYLAXIS OF CARDIAC DISORDERS. AMERICAN HOSPITAL SUPPLY CORP (US) 1983-04-25 EP disclosed
EP-0065963-A1 COMPOUNDS AND METHOD FOR TREATMENT OR PROPHYLAXIS OF CARDIAC DISORDERS. AMERICAN HOSPITAL SUPPLY CORP (US) 1982-12-08 EP disclosed
WO-1982001870-A1 COMPOUNDS AND METHOD FOR TREATMENT OR PROPHYLAXIS OF CARDIAC DISORDERS AMERICAN HOSPITAL SUPPLY CORP (US) 1982-06-10 WO disclosed
EP-0053434-A1 Compounds and method for treatment or prophylaxis of cardiac disorders AMERICAN HOSPITAL SUPPLY CORPORATION (US) 1982-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624164-B2 Synthetic thickeners incorporating non-reactive diluents GEMIN4, MAGT1, SETDB1 ALDH1A1 2580/4885CYP1A2 2558/4885CYP2C9 2128/4885
US-12590181-B2 Hydrophobically-modified associative thickener polymers process for the preparation and uses thereof PHOSPHO1, H1-10, H1-0 ALDH1A1 4014/4885CYP1A2 3354/4885CYP2C9 2530/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.