Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.52 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13352085 | 0.85 | GAA (0.59) | HPGDSMN1; SMN2LMNAHDAC3ALDH1A1 | |
| SCHEMBL19149894 | 0.84 | MMP1 (0.70) | MMP1HPGDMAPK14CA12CA1 | |
| SCHEMBL1222467 | 0.84 | MMP1 (0.74) | MMP1HPGDMAPK14CA12CA1 | |
| SCHEMBL13754242 | 0.84 | HPGD (0.66) | MMP1HPGDMAPK14CA12CA1 | |
| SCHEMBL8947296 | 0.83 | MMP1 (0.68) | MMP1HPGDMAPK14CA12CA1 | |
| SCHEMBL1222283 | 0.82 | SMN1; SMN2 (0.65) | MMP1HPGDMAPK14CA12CA1 | |
| SCHEMBL19130710 | 0.81 | MMP1 (0.65) | MMP1HPGDMAPK14CA12CA1 | |
| SCHEMBL25363727 | 0.79 | MMP1 (0.76) | MMP1HPGDMAPK14CA12CA1 | |
| SCHEMBL7163404 | 0.78 | MMP2 (0.62) | MMP1HPGDCA12CA1CA2 | |
| Diphenylether SCHEMBL27521612 | 0.78 | LTA4H (0.55) | HPGDSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015117196-A1 | ANTIBACTERIAL AGENTS | THE UNIVERSITY OF QUEENSLAND (AU) | 2015-08-13 | — | — | WO | disclosed |