Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.58 |
| ▸ | ABAT | P80404 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.58 |
| ▸ | FDPS | P14324 | 1/20 | 0.54 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27773256 | 0.85 | APP (0.65) | APPALDH1A1TSHRTRIM24HPGD | |
| SCHEMBL29953005 | 0.82 | APP (0.45) | APPALDH1A1TSHRTRIM24HPGD | |
| SCHEMBL6640602 | 0.80 | ALDH1A1 (0.56) | ALDH1A1TSHRTRIM24HPGDALDH5A1 | |
| SCHEMBL11898470 | 0.78 | TTR (0.55) | APPALDH1A1TSHRTRIM24HPGD | |
| SCHEMBL20059179 | 0.78 | FDPS (0.51) | APPALDH1A1TSHRTRIM24HPGD | |
| SCHEMBL12948238 | 0.78 | ALDH1A1 (0.50) | APPALDH1A1TSHRTRIM24HPGD | |
| SCHEMBL29681880 | 0.78 | ALDH1A1 (0.42) | APPALDH1A1TSHRTRIM24HPGD | |
| 3,4-Dimethoxybenzaldehyde SCHEMBL5308959 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TSHRTRIM24HPGDALDH5A1 | |
| 3,4-Dimethoxybenzaldehyde SCHEMBL25202 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TSHRTRIM24HPGDALDH5A1 | |
| 3,4-Dimethoxybenzaldehyde SCHEMBL1330962 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TSHRTRIM24HPGDALDH5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118930497-A | Conjugate of c-di-GMP G-quadruplex inducer and NO donor and application thereof in antibacterial biomembrane | 暨南大学 | 2024-11-12 | — | — | CN | disclosed |
| WO-2015120390-A1 | PHARMACEUTICAL COMPOUNDS | ONCOTHYREON INC. (US) | 2015-08-13 | — | — | WO | disclosed |