Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.58 |
| ▸ | FDPS | P14324 | 1/20 | 0.54 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.53 |
| ▸ | ABAT | P80404 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17002500 | 0.85 | APP (0.65) | APPALDH1A1TSHRAOX1FDPS | |
| SCHEMBL19595290 | 0.84 | ALDH1A1 (0.61) | APPALDH1A1TSHRAOX1FDPS | |
| SCHEMBL1121629 | 0.81 | ALDH1A1 (0.58) | APPALDH1A1TSHRAOX1FDPS | |
| SCHEMBL29951436 | 0.80 | ALDH1A1 (0.56) | ALDH1A1TSHRAOX1FDPSTRIM24 | |
| SCHEMBL6670831 | 0.80 | ALDH1A1 (0.56) | ALDH1A1TSHRAOX1FDPSTRIM24 | |
| SCHEMBL8386593 | 0.80 | ALDH1A1 (0.56) | APPALDH1A1TSHRAOX1FDPS | |
| SCHEMBL29953879 | 0.78 | ALDH1A1 (0.42) | APPALDH1A1TSHRAOX1FDPS | |
| 3,4-Dimethoxybenzaldehyde SCHEMBL1330962 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TSHRAOX1FDPSTRIM24 | |
| 3,4-Dimethoxybenzaldehyde SCHEMBL5308959 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TSHRAOX1FDPSTRIM24 | |
| 3,4-Dimethoxybenzaldehyde SCHEMBL25202 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TSHRAOX1FDPSTRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101602730-B | Substituted imidazole derivative | UNIV PEKING FOUNDER GROUP CO | 2013-06-19 | — | — | CN | disclosed |
| CN-101602730-A | The imdazole derivatives that replaces | FOUNDER GROUP (CN) | 2009-12-16 | — | — | CN | disclosed |