Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | BLM | P54132 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.50 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17124185 | 0.92 | MEN1 (0.72) | MEN1BLMKMT2ATHRBRECQL | |
| Trifluoroacetic Acid SCHEMBL17003722 | 0.89 | MEN1 (0.64) | MEN1BLMKMT2ATHRBRECQL | |
| SCHEMBL17003732 | 0.87 | MEN1 (0.52) | MEN1BLMKMT2ATHRBRECQL | |
| SCHEMBL21878574 | 0.83 | P2RY6 (0.65) | MEN1BLMKMT2ATHRBRECQL | |
| SCHEMBL12418857 | 0.81 | MEN1 (0.59) | MEN1BLMKMT2ATHRBRECQL | |
| Acetic Acid SCHEMBL17003739 | 0.81 | MEN1 (0.65) | MEN1BLMKMT2ATHRBRECQL | |
| Trifluoroacetic Acid SCHEMBL22204560 | 0.80 | P2RY6 (0.62) | MEN1BLMKMT2ATHRBRECQL | |
| SCHEMBL17012725 | 0.78 | MEN1 (0.53) | MEN1BLMKMT2ATHRBRECQL | |
| SCHEMBL17124186 | 0.78 | MEN1 (0.69) | MEN1BLMKMT2ATHRBRECQL | |
| SCHEMBL14013408 | 0.77 | MEN1 (0.79) | MEN1BLMKMT2ATHRBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150276751-A1 | REAGENT FOR IMAGING INTRACELLULAR ACETYLATION | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2015-10-01 | — | — | US | disclosed |
| EP-2907877-A1 | REAGENT FOR IMAGING INTRACELLULAR ACETYLATION | Japan Science and Technology Agency (JP) | 2015-08-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150276751-A1 | REAGENT FOR IMAGING INTRACELLULAR ACETYLATION | ACAT1, ACAT2, ACAA2 | MEN1 4111/4885BLM 4026/4885KMT2A 2532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.