Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA9 | Q16790 | 3/20 | 0.52 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.50 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | GBA1 | P04062 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10293759 | 0.93 | P2RY6 (0.64) | P2RY6MEN1THRBRECQLBLM | |
| SCHEMBL22204520 | 0.90 | P2RY6 (0.69) | P2RY6MEN1THRBRECQLBLM | |
| SCHEMBL31756958 | 0.90 | P2RY6 (0.69) | P2RY6MEN1THRBRECQLBLM | |
| SCHEMBL12716296 | 0.87 | P2RY6 (0.62) | P2RY6MEN1THRBRECQLBLM | |
| SCHEMBL29631727 | 0.87 | P2RY6 (0.65) | P2RY6MEN1THRBRECQLBLM | |
| SCHEMBL18286480 | 0.86 | P2RY6 (0.60) | P2RY6MEN1THRBRECQLBLM | |
| SCHEMBL18713197 | 0.86 | MEN1 (0.62) | P2RY6MEN1THRBRECQLBLM | |
| SCHEMBL25343641 | 0.85 | P2RY6 (0.65) | P2RY6MEN1THRBRECQLBLM | |
| SCHEMBL14049043 | 0.85 | P2RY6 (0.67) | P2RY6MEN1THRBRECQLBLM | |
| SCHEMBL14263356 | 0.85 | P2RY6 (0.60) | P2RY6MEN1THRBRECQLBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11512084-B2 | Degradation agent using autophagic mechanism of damaged mitochondria | TOHOKU UNIVERSITY (JP) | 2022-11-29 | — | — | US | disclosed |
| US-20200223848-A1 | DEGRADATION AGENT USING AUTOPHAGIC MECHANISM OF DAMAGED MITOCHONDRIA | TOHOKU UNIVERSITY (JP) | 2020-07-16 | — | — | US | disclosed |
| EP-3679935-A1 | DEGRADATION AGENT USING AUTOPHAGIC MECHANISM OF DAMAGED MITOCHONDRIA | Tohoku University (JP) | 2020-07-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200223848-A1 | DEGRADATION AGENT USING AUTOPHAGIC MECHANISM OF DAMAGED MITOCHONDRIA | HSPA9, ATG7, TFAM | P2RY6 3979/4885MEN1 3688/4885THRB 2718/4885 |
| US-11512084-B2 | Degradation agent using autophagic mechanism of damaged mitochondria | HSPA9, ATG7, TFAM | P2RY6 3979/4885MEN1 3688/4885THRB 2718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.