SCHEMBL170039

SCHEMBL170039

C=CCNOC(=O)C(=C)CC=C

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MAPT P10636 1/20 0.32
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9058758 0.82 KMT2A (0.33) TSHRSMN1; SMN2MAPTKMT2A
SCHEMBL1435127 0.78 ALDH1A1 (0.44) TSHRSMN1; SMN2MAPTKMT2A
SCHEMBL10676974 0.77 TSHR (0.35) TSHRSMN1; SMN2MAPTKMT2A
SCHEMBL18448671 0.76 MAPT (0.34) MAPT
SCHEMBL1950793 0.74
SCHEMBL244290 0.73 ALDH1A1 (0.31) TSHR
SCHEMBL1489998 0.73 TSHR (0.39) TSHRSMN1; SMN2MAPTKMT2A
SCHEMBL5466294 0.73 TSHR (0.44) TSHRSMN1; SMN2MAPT
SCHEMBL11500277 0.73 KMT2A (0.40) TSHRSMN1; SMN2MAPTKMT2A
SCHEMBL28109254 0.72 ALDH1A1 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108290359-A contact lens packaging solution 诺华股份有限公司 2018-07-17 CN claimed
EP-1330502-B1 COATING COMPOSITION VALSPAR SOURCING INC (US) 2004-06-02 EP claimed
EP-1330502-A2 COATING COMPOSITION Valspar Sourcing, Inc. (US) 2003-07-30 EP claimed
WO-2002036692-A2 COATING COMPOSITION VALSPAR SOURCING, INC. (US) 2002-05-10 WO claimed
EP-0178096-B2 Improved process for matching color of paint to a colored surface DU PONT (US) 1993-10-27 EP claimed
EP-0178096-B1 IMPROVED PROCESS FOR MATCHING COLOR OF PAINT TO A COLORED SURFACE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-03-14 EP claimed
US-4692481-A REFINISHING OR REPAIR OF AUTOMOBILES AND TRUCKS; MATCHING PRINTS CONTAINING METALLIC FLAKE PIGMENTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-09-08 US claimed
EP-0178096-A2 Improved process for matching color of paint to a colored surface E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-04-16 EP claimed
US-20200163863-A1 WATER-RESISTANT COSMETIC MEANS FOR TEMPORARILY CHANGING THE COLOUR OF KERATIN-CONTAINING MATERIALS II HENKEL AG & CO. KGAA (DE) 2020-05-28 US disclosed
CN-105050705-B The microcapsules of spray drying 恩盖普有限公司 2018-07-27 CN disclosed
CN-108290359-A contact lens packaging solution 诺华股份有限公司 2018-07-17 CN disclosed
EP-1776161-B1 COSMETIC OR DERMOPHARMACEUTICAL COMPOSITION COMPRISING AT LEAST ONE UDP GLUCURONOSYL TRANSFERASE (UGT) ENZYMES INDUCER SEDERMA S A S (FR) 2016-10-26 EP disclosed
EP-1463793-B1 MIXTURES OF QUATERNARY COMPOUNDS CRODA INC (US) 2016-10-19 EP disclosed
CN-105050705-A Spray drying microcapsules APPVION INC 2015-11-11 CN disclosed
EP-0351364-A2 Dimethylacrylamide-copolymer hydrogels with high oxygen permeability CIBA-GEIGY AG (CH) 1990-01-17 EP disclosed
WO-1990000045-A1 AUTOPHOBIC SILICONE COPOLYOLS IN HAIRSPRAY COMPOSITIONS S.C. JOHNSON & SON, INC. (US) 1990-01-11 WO disclosed
US-4871529-A TRIMETHYLSILOXY ENDCAPPED POLYDIMETHYLSILOXANE AND POLYETHERSILOXANES; CONTRACTION ON HAIR S. C. JOHNSON & SON, INC. (US) 1989-10-03 US disclosed
US-4692481-A REFINISHING OR REPAIR OF AUTOMOBILES AND TRUCKS; MATCHING PRINTS CONTAINING METALLIC FLAKE PIGMENTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-09-08 US disclosed
EP-0178096-A2 Improved process for matching color of paint to a colored surface E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-04-16 EP disclosed
US-3990381-A Hydrophilic polymer coating for underwater structures NATIONAL PATENT DEVELOPMENT CORPORATION (US) 1976-11-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200163863-A1 WATER-RESISTANT COSMETIC MEANS FOR TEMPORARILY CHANGING THE COLOUR OF KERATIN-CONTAINING MATERIALS II KRT18, CUTA, DSG1 TSHR 3607/4885SMN1; SMN2 2932/4885MAPT 2411/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.