Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | TPO | P07202 | 1/20 | 0.33 |
| ▸ | EPX | P11678 | 1/20 | 0.33 |
| ▸ | LPO | P22079 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17004213 | 0.84 | CHRNB2 (0.41) | CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL17004264 | 0.83 | CHRNB2 (0.39) | CHRNB2CHRNA4CHRNA7 | |
| Hydrochloric Acid SCHEMBL3829131 | 0.80 | NSD2 (0.31) | CHRNA7 | |
| SCHEMBL17004251 | 0.78 | MAPT (0.45) | CHRNB2CHRNA4 | |
| SCHEMBL3825645 | 0.75 | CHRNB2 (0.41) | CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL17004328 | 0.73 | CHRNB2 (0.35) | CHRNB2CHRNA4 | |
| SCHEMBL17004234 | 0.71 | CHRNA7 (0.42) | CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL29604064 | 0.71 | KCNH2 (0.47) | CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL17004276 | 0.71 | KCNH2 (0.47) | CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL17004329 | 0.70 | LNPEP (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099795-B1 | AZAADAMANTANE DERIVATIVES AND THEIR USES AS NICOTINIC ACETYLCHOLINE RECEPTORS LIGANDS | ABBVIE BAHAMAS LTD (BS) | 2015-08-19 | — | — | EP | disclosed |