Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17004213 | 0.84 | CHRNB2 (0.41) | CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL17004191 | 0.83 | MPO (0.33) | CHRNB2CHRNA4CHRNA7 | |
| Hydrochloric Acid SCHEMBL3829131 | 0.80 | NSD2 (0.31) | CHRNA7 | |
| SCHEMBL17004328 | 0.79 | CHRNB2 (0.35) | CHRNB2CHRNA4 | |
| SCHEMBL17004251 | 0.78 | MAPT (0.45) | CHRNB2CHRNA4 | |
| SCHEMBL3825645 | 0.75 | CHRNB2 (0.41) | CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL17004248 | 0.75 | HMOX1 (0.33) | — | |
| SCHEMBL17004185 | 0.74 | HCRTR1 (0.39) | — | |
| SCHEMBL17004290 | 0.74 | CHRNB2 (0.40) | CHRNB2CHRNA4 | |
| SCHEMBL17004234 | 0.71 | CHRNA7 (0.42) | CHRNB2CHRNA4CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099795-B1 | AZAADAMANTANE DERIVATIVES AND THEIR USES AS NICOTINIC ACETYLCHOLINE RECEPTORS LIGANDS | ABBVIE BAHAMAS LTD (BS) | 2015-08-19 | — | — | EP | disclosed |