Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17004248 | 0.82 | HMOX1 (0.33) | — | |
| SCHEMBL17004198 | 0.81 | FURIN (0.40) | RET | |
| SCHEMBL17004295 | 0.77 | CHRNB2 (0.41) | ALDH1A1 | |
| SCHEMBL17004243 | 0.77 | S1PR4 (0.33) | — | |
| SCHEMBL17004184 | 0.74 | MEN1 (0.31) | HTT | |
| SCHEMBL17004242 | 0.74 | CHRM2 (0.54) | — | |
| SCHEMBL20068851 | 0.73 | RET (0.34) | RET | |
| SCHEMBL20147708 | 0.73 | RET (0.34) | RET | |
| SCHEMBL17004311 | 0.73 | TRPC3 (0.35) | — | |
| SCHEMBL3825645 | 0.73 | CHRNB2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099795-B1 | AZAADAMANTANE DERIVATIVES AND THEIR USES AS NICOTINIC ACETYLCHOLINE RECEPTORS LIGANDS | ABBVIE BAHAMAS LTD (BS) | 2015-08-19 | — | — | EP | disclosed |