Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.30 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.30 |
| ▸ | CHRNG | P07510 | 2/20 | 0.30 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.30 |
| ▸ | CHRND | Q07001 | 2/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17004295 | 0.83 | CHRNB2 (0.41) | KDM1A | |
| SCHEMBL17004253 | 0.77 | ALDH1A1 (0.33) | — | |
| SCHEMBL17004198 | 0.75 | FURIN (0.40) | HCRTR1HCRTR2 | |
| SCHEMBL17004201 | 0.75 | HCRTR1 (0.34) | HCRTR1HCRTR2 | |
| SCHEMBL3825645 | 0.71 | CHRNB2 (0.41) | CHRNB4CHRNA3CHRNA1CHRNGCHRNB1 | |
| SCHEMBL17004248 | 0.71 | HMOX1 (0.33) | — | |
| SCHEMBL17004264 | 0.70 | CHRNB2 (0.39) | CHRNA7 | |
| SCHEMBL17004185 | 0.70 | HCRTR1 (0.39) | HCRTR1HCRTR2 | |
| SCHEMBL17004328 | 0.69 | CHRNB2 (0.35) | CHRNB4CHRNA3 | |
| SCHEMBL17004249 | 0.69 | CHRNB2 (0.34) | CHRNB4CHRNA3CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099795-B1 | AZAADAMANTANE DERIVATIVES AND THEIR USES AS NICOTINIC ACETYLCHOLINE RECEPTORS LIGANDS | ABBVIE BAHAMAS LTD (BS) | 2015-08-19 | — | — | EP | disclosed |