SCHEMBL1700677

SCHEMBL1700677

NS(=O)(=O)c1ccc(CCc2ccccc2)cc1

nearest known ligand 0.76

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA2 P00918 18/20 0.76
CA1 P00915 15/20 0.76
CA12 O43570 9/20 0.76
CA4 P22748 5/20 0.76
CA9 Q16790 9/20 0.69
CA14 Q9ULX7 4/20 0.69
CA7 P43166 8/20 0.68
CA13 Q8N1Q1 2/20 0.68
CA5A P35218 6/20 0.67
CA5B Q9Y2D0 6/20 0.67
CA6 P23280 3/20 0.67
HSD17B10 Q99714 1/20 0.66
ALDH1A1 P00352 1/20 0.64
CA3 P07451 1/20 0.62
PLA2G7 Q13093 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10690610 0.87 CA2 (0.89) CA2CA1CA12CA4CA9
SCHEMBL23202943 0.87 CA1 (1.00) CA2CA1CA12CA4CA9
Benzenesulfonamide SCHEMBL7207114 0.83 CA1 (0.74) CA2CA1CA12CA4CA9
Sulfanilamide SCHEMBL27483111 0.83 CA1 (0.72) CA2CA1CA12CA4CA9
SCHEMBL11119183 0.82 CA1 (0.65) CA2CA1CA12CA4CA9
SCHEMBL28802276 0.82 CA1 (0.59) CA2CA1CA12CA4CA9
SCHEMBL22029399 0.81 CA2 (0.75) CA2CA1CA12CA4CA9
SCHEMBL142107 0.80 CA2 (1.00) CA2CA1CA12CA4CA9
SCHEMBL1804221 0.80 CA2 (0.69) CA2CA1CA12CA4CA9
SCHEMBL11730795 0.80 CA2 (0.69) CA2CA1CA12CA4CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4146480-A1 HEAT-SENSITIVE RECORDING MATERIAL Koehler Innovation & Technology GmbH (DE) 2023-03-15 EP disclosed
EP-4037909-A1 POLYMORPHIC FORMS OF N-(4-((4-(3-PHENYLUREIDO)PHENYL)SULFONYL)PHENYL)BENZOLSULFONAMIDE Koehler Paper SE (DE) 2022-08-10 EP disclosed
CN-109526219-B Benzenesulfonamides and their use as therapeutic agents 泽农医药公司 2021-03-12 CN disclosed
CN-110526842-A A kind of preparation method and products thereof of water phase alkynes aminated compounds UNIV NANJING FORESTRY 2019-12-03 CN disclosed
CN-110267939-A Thermal recording medium 奥古斯特科勒纸厂欧洲公司 2019-09-20 CN disclosed
CN-108440345-A A kind of preparation method of sulfamide compound 西北师范大学 2018-08-24 CN disclosed
WO-2011137485-A1 MEDIA AND METHODS FOR CELL CULTURE SYDNEY IVF LIMITED (AU) 2011-11-10 WO disclosed
WO-2006075955-A1 PYRAZOLYL ACYLSULFONAMIDE DERIVATIVES AS ENDOTHELIN CONVERTING ENZYME INHIBITORS AND USEFUL IN THE TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE ASTRAZENECA AB (SE) 2006-07-20 WO disclosed