SCHEMBL10690610

SCHEMBL10690610

NS(=O)(=O)c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.89

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA2 P00918 20/20 0.89
CA1 P00915 19/20 0.89
CA9 Q16790 15/20 0.89
CA12 O43570 12/20 0.89
CA14 Q9ULX7 5/20 0.89
CA4 P22748 6/20 0.65
CA7 P43166 7/20 0.62
CA5A P35218 4/20 0.62
CA5B Q9Y2D0 4/20 0.62
CA6 P23280 2/20 0.62
CA13 Q8N1Q1 2/20 0.62
CA3 P07451 1/20 0.62
PLA2G7 Q13093 1/20 0.62
MAPT P10636 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL309694 0.91 CA2 (0.73) CA2CA1CA9CA12CA14
Sulfamide SCHEMBL5585371 0.89 CA2 (0.70) CA2CA1CA9CA12CA14
SCHEMBL1700677 0.87 CA2 (0.76) CA2CA1CA9CA12CA14
SCHEMBL22233466 0.82 CA1 (0.62) CA2CA1CA9CA12CA14
SCHEMBL27901606 0.82 CA1 (0.62) CA2CA1CA9CA12CA14
SCHEMBL27816697 0.81 CA2 (0.75) CA2CA1CA9CA12CA14
SCHEMBL14937572 0.80 CA1 (0.63) CA2CA1CA9CA12CA14
Benzenesulfonamide SCHEMBL11870525 0.80 CA2 (0.60) CA2CA1CA9CA12CA14
SCHEMBL27959272 0.79 CA2 (0.59) CA2CA1CA9CA12CA14
SCHEMBL23202943 0.79 CA1 (1.00) CA2CA1CA9CA12CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250367649-A1 PHOTOCATALYSTS, PREPARATION AND USE THEREOF THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIV (CA) 2025-12-04 US disclosed
CN-109369506-B Method for selectively N-methylating secondary amide 广东石油化工学院 2022-05-31 CN disclosed
CN-1854128-B Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds MASSACHUSETTS INST TECHNOLOGY 2012-05-16 CN disclosed
WO-2008076778-A1 4-AMINO-1H-PYRIMIDIN-2-ONE BASED COMPOUNDS, COMPOSITIONS COMPRISING THEM, AND METHODS OF THEIR USE LEXICON PHARMACEUTICALS, INC. (US) 2008-06-26 WO disclosed
CN-1326519-C Compounds and uses thereof for decreasing activity of hormone-sensitive lipase NOVO NORDISK AS (DK) 2007-07-18 CN disclosed
CN-1602191-A Compounds and uses thereof for decreasing activity of hormone-sensitive lipase NOVO NORDISK AS (DK) 2005-03-30 CN disclosed
CN-1264365-A 3-benzoylindole derivatives and drugs containing the same ZERIA PHARM CO LTD (JP) 2000-08-23 CN disclosed
EP-0260833-A2 Process for producing polyamide acid having siloxane bonds and polyimide having siloxane bonds and isoindoloquinazolinedione rings HITACHI CHEMICAL COMPANY (JP) 1988-03-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250367649-A1 PHOTOCATALYSTS, PREPARATION AND USE THEREOF PPOX, AOX1, CYP3A7 CA2 1987/4885CA1 1091/4885CA9 353/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.