SCHEMBL142107

SCHEMBL142107

NCCc1ccc(S(N)(=O)=O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 17/20 1.00
CA1 P00915 10/20 1.00
CA12 O43570 7/20 1.00
CA9 Q16790 6/20 1.00
CA4 P22748 6/20 1.00
CA6 P23280 5/20 1.00
CA5A P35218 5/20 1.00
CA7 P43166 5/20 1.00
CA14 Q9ULX7 5/20 1.00
CA5B Q9Y2D0 5/20 1.00
F2 P00734 2/20 0.67
TMPRSS4 Q9NRS4 2/20 0.67
TSHR P16473 2/20 0.67
TP53 P04637 1/20 0.67
CYP1A2 P05177 1/20 0.67
CYP2D6 P10635 1/20 0.67
MAPT P10636 1/20 0.65
SMN1; SMN2 Q16637 1/20 0.62
HTR6 P50406 1/20 0.62
USP2 O75604 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2352021 0.98 CA2 (0.96) CA2CA1CA12CA9CA4
Hydrochloric Acid SCHEMBL27515376 0.96 CA2 (0.92) CA2CA1CA12CA9CA4
SCHEMBL12614485 0.89 CA2 (0.79) CA2CA1CA12CA9CA4
Isothiocyanate SCHEMBL29213995 0.89 CA2 (0.79) CA2CA1CA12CA9CA4
SCHEMBL9683336 0.87 CA2 (0.77) CA2CA1CA12CA9CA4
Benzenesulfonamide SCHEMBL7207114 0.85 CA1 (0.74) CA2CA1CA12CA9CA4
Hydrochloric Acid SCHEMBL15193100 0.85 CA2 (0.74) CA2CA1CA12CA9CA4
Sulfanilamide SCHEMBL27483111 0.85 CA1 (0.72) CA2CA1CA12CA9CA4
SCHEMBL6680951 0.84 HTR6 (0.84) CA2CA1CA12CA9CA4
SCHEMBL1804221 0.82 CA2 (0.69) CA2CA1CA12CA9CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1339 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120157773-A Chimeric antigen receptor, nucleic acid molecule, CAR-Ms and application thereof 山东大学 2025-06-17 CN claimed
CN-119823036-A HYNIC modified 4- (2-aminoethyl) benzenesulfonamide derivative and application thereof 北京师范大学 2025-04-15 CN claimed
CN-119632952-A Preparation method of tumor microenvironment regulation type nano drug delivery system, product and application thereof 杭州市第一人民医院(西湖大学附属杭州市第一人民医院) 2025-03-18 CN claimed
CN-119264173-A Si rhodamine derivative for hypoxia imaging and preparation method and application thereof 河南师范大学 2025-01-07 CN claimed
CN-119060130-A Self-assembled nano material for targeting hypoxic tumor cell membrane to prevent exosome from escaping, and preparation method and application thereof 国家纳米科学中心 2024-12-03 CN claimed
CN-118315677-B Wide-temperature-range electrolyte and preparation method and application thereof 河北省科学院能源研究所 2024-10-01 CN claimed
CN-118315677-A Wide-temperature-range electrolyte and preparation method and application thereof 河北省科学院能源研究所 2024-07-09 CN claimed
CN-118059250-A Nanometer medicine for destroying crosstalk and preparation method and application thereof 中国医学科学院放射医学研究所 2024-05-24 CN claimed
CN-114614058-B Thin-layer composite proton exchange membrane and preparation method and application thereof 中国石油化工股份有限公司 2024-05-07 CN claimed
CN-117732437-A Preparation and drug target identification application of switchable sulfhydryl functional magnetic silica nanoparticle 北京青莲百奥生物科技有限公司 2024-03-22 CN claimed
WO-2002064598-A1 THIENO'2,3-D PYRIMIDINDIONE DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS WARNER-LAMBERT COMPANY LLC (US) 2002-08-22 WO claimed
US-20020058788-A1 Facile deprotection of Fmoc protected amino groups DISCOVERY PARTNERS INTERNATIONAL, INC. 2002-05-16 US claimed
US-6068989-A Method and dry analytical element for determination of bicarbonate ion in liquid FUJI PHOTO FILM CO., LTD. (JP) 2000-05-30 US claimed
WO-2000006525-A9 SYNTHESIS OF COMBINATORIAL LIBRARIES OF COMPOUNDS REMINISCENT OF NATURAL PRODUCTS HARVARD COLLEGE (US) 2000-04-20 WO claimed
WO-2000006525-A2 SYNTHESIS OF COMBINATORIAL LIBRARIES OF COMPOUNDS REMINISCENT OF NATURAL PRODUCTS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2000-02-10 WO claimed
US-5945520-A RESIN OF SOLID SUPPORT MATRIX, SPACER ARM AND IONIZABLE FUNCTIONALITY; SPECIFICALLY DESIGNED TO BIND THE TARGET COMPOUND FROM AN AQUEOUS SOLUTION AT BOTH A LOW AND HIGH IONIC STRENGTH MASSEY UNIVERSITY (NZ) 1999-08-31 US claimed
US-5652348-A SOLID SUPPORT MATRIX, IONIZABLE LIGANDS SELECTED RELATIVE TO TARGET COMPOUND MASSEY UNIVERSITY (NZ) 1997-07-29 US claimed
EP-0783366-A1 CHROMATOGRAPHIC RESINS AND METHODS FOR USING SAME MASSEY UNIVERSITY (NZ) 1997-07-16 EP claimed
WO-1996009116-A1 CHROMATOGRAPHIC RESINS AND METHODS FOR USING SAME MASSEY UNIVERSITY (NZ) 1996-03-28 WO claimed
EP-0443560-A2 HIV protease inhibitors BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1991-08-28 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020058788-A1 Facile deprotection of Fmoc protected amino groups DNPEP, LNPEP, NPEPPS CA2 3928/4885CA1 1001/4885CA12 2200/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.