SCHEMBL1700737

SCHEMBL1700737

O=C(CCCCCNc1ccc([N+](=O)[O-])cc1[N+](=O)[O-])ON1C(=O)CCC1=O

nearest known ligand 0.60

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.60
KDM4E B2RXH2 1/20 0.60
ALDH1A1 P00352 4/20 0.59
POLB P06746 5/20 0.57
PKM P14618 1/20 0.49
PRSS1 P07477 3/20 0.44
KMT2A Q03164 5/20 0.43
HCAR3 P49019 2/20 0.43
MEN1 O00255 4/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30060749 1.00 MAPT (0.60) MAPTKDM4EALDH1A1POLBPKM
SCHEMBL13248196 0.87 MAPT (0.52) MAPTKDM4EALDH1A1POLBPKM
SCHEMBL28933688 0.86 KAT2B (0.49) MAPTKDM4EALDH1A1POLBPRSS1
SCHEMBL4427844 0.86 MAPT (0.51) MAPTKDM4EALDH1A1POLBPKM
SCHEMBL2779876 0.85 MAPT (0.49) MAPTKDM4EALDH1A1POLBPKM
SCHEMBL29356494 0.84 MAPT (0.42) MAPTKDM4EALDH1A1POLBPRSS1
SCHEMBL13583637 0.84 MAPT (0.42) MAPTKDM4EALDH1A1POLBPRSS1
SCHEMBL27343040 0.82 MAPT (0.73) MAPTKDM4EALDH1A1POLBPKM
SCHEMBL596079 0.81 GSTM2 (0.61) KMT2AMEN1
SCHEMBL13795300 0.81 GSTM2 (0.61) KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11619630-B2 Immunochromatography device SANWA KAGAKU KENKYUSHO CO., LTD. (JP) 2023-04-04 US disclosed
US-20200333336-A1 IMMUNOCHROMATOGRAPHY DEVICE SANWA KAGAKU KENKYUSHO CO., LTD. (JP) 2020-10-22 US disclosed
CN-111480078-A Immunochromatographic device 株式会社三和化学研究所 2020-07-31 CN disclosed
US-10144849-B2 Polishing composition and polishing method using the same FUJIMI INCORPORATED (JP) 2018-12-04 US disclosed
EP-2566334-B1 CONTROLLED DRUG RELEASE FROM SOLID SUPPORTS PROLYNX LLC (US) 2018-04-18 EP disclosed
EP-2566335-B1 CONTROLLED RELEASE OF ACTIVE COMPOUNDS FROM MACROMOLECULAR CONJUGATES PROLYNX LLC (US) 2016-06-29 EP disclosed
US-8946405-B2 Controlled release from solid supports PROLYNX LLC (US) 2015-02-03 US disclosed
US-8754190-B2 Controlled release from macromolecular conjugates PROLYNX LLC (US) 2014-06-17 US disclosed
US-8703907-B2 Controlled drug release from dendrimers PROLYNX LLC (US) 2014-04-22 US disclosed
US-20130123461-A1 CONTROLLED DRUG RELEASE FROM DENDRIMERS PROLYNX LLC (US) 2013-05-16 US disclosed
US-20090197848-A1 Synthetic mimics of mammalian cell surface receptors: method and compositions THE PENN STATE RESEARCH FOUNDATION (US) 2009-08-06 US disclosed
US-20090197848-A1 Synthetic mimics of mammalian cell surface receptors: method and compositions THE PENN STATE RESEARCH FOUNDATION (US) 2009-08-06 US disclosed
US-7514400-B2 Synthetic mimics of mammalian cell surface receptors: method and compositions THE PENN STATE RESEARCH FOUNDATION (US) 2009-04-07 US disclosed
US-7514400-B2 Synthetic mimics of mammalian cell surface receptors: method and compositions THE PENN STATE RESEARCH FOUNDATION (US) 2009-04-07 US disclosed
US-20060229235-A1 Synthetic mimics of mammalian cell surface receptors: method and compositions THE PENN STATE RESEARCH FOUNDATION (US) 2006-10-12 US disclosed
US-5614368-A LABELLED-HAPTEN WITH POLYPEPTIDES FOR DIAGNOSIS OF ANTIGENS AND ANTIBODIES MOLECULAR DEVICES CORPORATION (US) 1997-03-25 US disclosed
US-5256395-A Drug delivery by administering a receptor binding assay having a dual preferential monoclonal antibody conjugating with predetermined haptens IMMUNOTECH PARTNERS (FR) 1993-10-26 US disclosed
US-5180828-A Proteins and polynucleotides, nondestructive MOLECULAR DEVICES CORPORATION (US) 1993-01-19 US disclosed
EP-0263046-B1 AFFINITY ENHANCEMENT IMMUNOLOGICAL REAGENTS FOR DETECTION AND KILLING OF SPECIFIC TARGET CELLS IMMUNOTECH PARTNERS (FR) 1992-04-15 EP disclosed
EP-0263046-A1 Affinity enhancement immunological reagents for detection and killing of specific target cells IMMUNOTECH PARTNERS (FR) 1988-04-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130123461-A1 CONTROLLED DRUG RELEASE FROM DENDRIMERS SLC43A1, SLC47A1, SLC47A2 MAPT 1847/4885KDM4E 3717/4885ALDH1A1 2780/4885
US-20090197848-A1 Synthetic mimics of mammalian cell surface receptors: method and compositions MSR1, M6PR, ASGR1 MAPT 4740/4885KDM4E 4618/4885ALDH1A1 4719/4885
US-20060229235-A1 Synthetic mimics of mammalian cell surface receptors: method and compositions MSR1, M6PR, ASGR1 MAPT 4740/4885KDM4E 4618/4885ALDH1A1 4719/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.